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591. α-D-2’-Deoxyadenosine: an irradiation product of canonical DNA and a component of anomeric nucleic acids. Crystal structure, packing and Hirshfeld surface analysis
Peter Leonard, Aigui Zhang, Simone Budow-Busse, Constantin Daniliuc and Frank Seela, Acta Cryst. C, 2024, 21-29.
590. Nucleobase-Functionalized 7-Deazaisoguanine and 7-Deazapurin-2,6-diamine Nucleosides: Halogenation, Cross-Coupling and Cycloaddition
Zhenqiang Xia, Dasharath Kondhare, Somnath Chandankar, Sachin Ingale, Peter Leonard and Frank Seela, J. Org. Chem., 2024, 89, 807-822.
589. Purine DNA Constructs Designed to Expand the Genetic Code: Functionalization, Impact of Ionic Forms, and Molecular Recognition of 7‑Deazaxanthine−7-Deazapurine-2,6-diamine Base Pairs and Their Purine Counterparts
Somnath S. Chandankar, Dasharath Kondhare, Peter Leonard, and Frank Seela, J. Org. Chem., 2023, 88, 13149.
588. Watson-Crick Base Pairs with Protecting Groups: The 2-Amino Groups of Purine- and 7-Deazapurine-2,6-diamine as Target Sites for DNA Functionalization by Selective Nucleobase Acylation
Dasharath Kondhare, Xenia Heddinga, Peter Leonard and Frank Seela, Bioconjugate Chem., 2023, 34, 1290.
587. The 2’-C-Methylribonucleoside of 5-Aza-7-deaza-7-iodoguanine: Hydrogen and Halogen Bonding in Nucleoside Crystals, Synthesis and Physical Properties
Dasharath Kondhare, Xenia Heddinga, Simone Budow-Busse, Constantin Daniliuc and Frank Seela, Journal Molecular Structure, 2023, 1286, 135535.
586. The Base Pairs of Isoguanine and 8-Aza-7-deazaisoguanine with 5-Methylisocytosine as Targets for DNA Functionalization
Dasharath Kondhare, Peter Leonard and Frank Seela, Bioconjugate Chem., 2023, 34, 422-432.
585. DNA Strand Displacement with Base Pair Stabilizers: Purine-2,6-diamine and 8-Aza-7-bromo-7-deazapurine-2,6-diamine Oligonucleotides Invade Canonical DNA and New Fluorescent Pyrene Click Sensors Monitor the Reaction
Aigui Zhang, Dasharath Kondhare, Peter Leonard and Frank Seela, Chem. Eur. J., 2022, 28, e202202412.
584. Purine-Purine Base Pairs in Parallel DNA: β-D Anomeric 8-Aza-7-deazaisoguanine and 7-Functionalized Conjugates Form Stable Base Pairs with α-D
5-Aza-7-deaza-2’-deoxyguanosine
Aigui Zhang, Dasharath Kondhare, Peter Leonard and Frank Seela, Bioconjugate Chemistry, 2022, 33, 1796.
583. DNA with Purine-Purine Base Pairs: Size and Position of Isoguanine and 8-Aza-7-deazaisoguanine Clickable Residues Control the Molecular Recognition of Guanine and 5-Aza-7-deazaguanine
Dasharath Kondhare, Aigui Zhang, Peter Leonard and Frank Seela, J. Org. Chem., 2022, 87, 10630.
582. The 2'-deoxyribofuranoside of tetrahydro-3-phenyl-pyrimido[4,5-c]pyridazin-7-one: a bicyclic nucleoside with sugar residues in N and S conformation and its molecular recognition
Hui Mei, Simone Budow-Busse, Dasharath Kondhare, Henning Eickmeier, Hans Reuter and Frank Seela, Acta. Cryst. C, 2022, C78, 382-389.
581. Anomeric DNA Strand Displacement with α-D Oligonucleotides as Invaders and Ethidium Bromide as Fluorescence Sensor for Duplexes with α/β-, β/β- and α/α-D Configuration
Aigui Zhang, Dasharath Kondhare, Peter Leonard and Frank Seela, Chemistry Eur. J., 2022, 28, e202201394.
580. 8-Furyl-imidazolo-2’-deoxycytidine: crystal structure, packing, atropisomerism and fluorescence
Simone Budow-Busse, Sunit K. Jana, Dasharath Kondhare, Constantin Daniliuc and Frank Seela, Acta Cryst., 2022, C78, 141-147.
579. Anomeric DNA: Functionalization of α-D Anomers of 7-Deaza-2’-deoxyadenosine and 2’-Deoxyuridine with Clickable Side Chains and Click Adducts in Homochiral and Heterochiral Double Helices
Aigui Zhang, Peter and Frank Seela, Chem. Eur. J., 2022, 28, e202103872.
578. Isoguanine (2-Hydroxyadenine) and 2-Aminoadenine Nucleosides with an 8-Aza-7-deazapurine Skeleton: Synthesis and Functionalization with Fluorescent and Clickable Side Chains and Impact of 7-Substituents on Physical Properties
Dasharath Kondhare, Peter Leonard and Frank Seela, J. Org. Chem., 2021, 86, 14461.
577. Anomeric and Enantiomeric 2’-Deoxycytidines: Base Pair Stability in the Absence and Presence of Silver Ions
Aigui Zhang, Simone Budow-Busse, Peter Leonard and Frank Seela, Chem. Eur. J., 2021, 27, 10475.
576. The α-D-anomer of 2’-deoxycytidine: crystal structure, nucleoside conformation and Hirshfeld surface analysis
Simone Budow-Busse, Yingying Chai, Sebastian Lars Müller, Constantin Daniliuc and Frank Seela, Acta Cryst., 2021, C77.
575. 5-Aza-7-deazaguanine-Isoguanine and Guanine-Isoguanine Base Pairs in Watson-Crick DNA: The Impact of Purine Tracts, Clickable Dendritic Side Chains and Pyrene Adducts
Aigui Zhang, Dasharath Kondhare, Peter Leonard and Frank Seela, Chem. Eur. J., 2021, 27, 7453.
574. The 2-Amino Group of 8-Aza-7-deaza-7-bromopurine-2,6-diamine and Purine-2,6-diamine as Stabilizer for the Adenine-Thymine Base Pair in Heterochiral DNA with Strands in Anomeric Configuration
Yingying Chai, Dasharath Kondhare, Aigui Zhang, Peter Leonard and Frank Seela, Chem., Eur. J., 2021, 27, 2093.
573. Alkynylated and Dendronized 5-Aza-7-deazaguanine Nucleosides: Cross-Coupling with Tripropargylamine and Linear Alkynes, Click Functionalization and Fluorescence of Pyrene Adducts
Dasharath Kondhare, Aigui Zhang, Peter Leonard and Frank Seela, J. Org. Chem., 2020, 85, 10525.
572. Heterochiral DNA with Complementary Strands in α-D and β-D Configuration: H-Bonded and Silver Mediated Base Pairs with Impact of 7-Deazapurines Replacing Purines
Yingying Chai, Xiurong Guo, Peter Leonard , Frank Seela, Chem. Eur. J., 2020, 26, 13973-13989.
571. 7-Iodo-5-aza-7-deazaguanine Ribonucleoside: Crystal Structure, Physical Properties, Base Pair Stability and Functionalization
Dasharath Kondhare, Simone Budow-Busse, Constantin D. Daniliuc, Frank Seela, Acta Cryst. C, 2020, C76, 513.
570. Nucleobase Functionalized 5-Aza-7-deazaguanine Ribo- and 2'-Deoxyribonucleosides: Glycosylation, Pd-Assisted Cross-Coupling and Photophysical Properties
Peter Leonard, Dasharath Kondhare, Xenia Jentgens, Constantin Daniliuc and Frank Seela, J.Org.Chem., 2019, 84, 13313.
569. Silver Mediated Homochiral and Heterochiral α-dC/β-dC Base Pairs: Synthesis of α-dC via Glycosylation and Impact of Consecutive, Isolated and Multiple Metal Ion Pairs on DNA Stability
Yingying Chai, Peter Leonard, Xiurong Guo, and Frank Seela, Chem. Eur. J., 2019, 25, 16639.
568. Anomeric 5-Aza-7-deaza-2`-deoxyguanosines in Silver Ion Mediated Homo and Hybrid Base Pairs: Impact of Mismatch Structure, Helical Environment and Nucleobase Substituents on DNA Stability
Xinglong Zhou, Dashrath Kondhare, Peter Leonard, and Frank Seela, Chem. Eur. J., 2019, 25, 10408.
567. Crystal Structures of α-D and β-D Anomeric 2'-Deoxycytidines Decorated with Octadiynyl Side Chains: Hydrogen Bonding, Crystal Packing and Impact of Alkyne Residues on Physical Properties
Xinglong Zhou, Sebastian Lars Müller, Peter Leonard, Constantin Daniliuc, Yingying Chai, Simone Budow-Busse, and Frank Seela,, J. Mol. Struct., 2019, 37-46, 1190.
566. Functionalized Silver Ion Mediated α-dC‒β-dC Hybrid Base Pairs with Exceptional Stability: α-D 5-Iodo-2’-Deoxycytidine and Its Octadiynyl Derivative in Metal DNA
Sebastian Lars Müller, Xinglong Zhou, Peter Leonard, Oxana Korzhenko, Constantin Daniliuc, and Frank Seela, Chem. Eur. J., 2019, 25, 3077.
565. Nucleoside macrocycles formed by intramolecular click reaction: Efficient cyclization of pyrimidine nucleosides decorated with 5'-azido residues and 5-octadiynyl side chains
Jiang Liu, Peter Leonard, Sebastian L. Müller, Constantin Daniliuc and Frank Seela, Beilstein J. Org. Chem., 2018, 14, 2402.
564. Glycosylation of Pyrrolo[2,3-d]pyrimidines with 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose: Substituents and Protecting Groups Effecting the Synthesis of 7-Deazapurine Ribonucleosides
Sachin A. Ingale, Peter Leonard and Frank Seela, J. Org. Chem., 2018, 83, 8589.
563. Guanine and 8-Azaguanine in Anomeric DNA Hybrid Base Pairs: Stability, Fluorescence Sensing and Efficient Mismatch Discrimination with α-D-Nucleosides
Jiang Liu, Sachin A. Ingale and Frank Seela, Bioconjugate Chem., 2018, 29, 2265.
562. 5-Aza-7-deaza-2’-deoxyguanosine and 2'-Deoxycytidine form Programmable Silver-Mediated Base Pairs with Metal Ions in the Core of the DNA Double Helix
Xiurong Guo, Peter Leonard, Sachin A. Ingale, Jiang Liu, Hui Mei , Martha Sieg, Frank Seela, Chem. Eur. J., 2018, 24, 8883.
561. Gemcitabine, Pyrrologemcitabine and 2’-Fluoro- 2’-Deoxycytidines: Synthesis, Physical Properties and Impact of Sugar Fluorination on Silver Ion Mediated Base Pairing
Xiurong Guo, Peter Leonard, Sachin A. Ingale, F. Seela, Chem. Eur. J., 2017, 23, 17740.
560. Anomeric 2’-Deoxycytidines and Silver Ions: Hybrid Base Pairs with Greatly Enhanced Stability and Efficient DNA Mismatch Detection with α-dC
Xiurong Guo and Frank Seela, Chem. Eur. J., 2017, 23, 11776.
559. 8-Aza-2’-deoxyisoguanosine Forms Fluorescent Hydrogels whereas 8-Aza-2’-deoxyguanosine Assembles to Nucleoside Nanotubes
Hang Zhao, Dawei Jiang, Andreas H. Schäfer, Frank Seela, ChemPlusChem, 2017, 82, 778-784.
558. Silver Mediated Base Pairs in DNA Incorporating Purines, 7-Deazapurines and 8-Aza-7-deazapurines: The Impact of Reduced Nucleobase Binding Sites and Altered Glycosylation Position
Hang Zhao, Peter Leonard, Xiurong Guo, Haozhe Yang, and Frank Seela, Chem. Eur. J., 2017, 23, 5529.
557. Supramolecular Isoguanosine Assemblies form Hydrogels with Excellent Long-term Stability
Hang Zhao, Andreas H. Schäfer, Frank Seela, ChemPlusChem, 2017, 82, 826-833.
556. MercuryII-mediated base pairs in DNA: unexpected behavior in metal ion binding and duplex stability induced by 2'-deoxyuridine 5-substituents
Xiurong Guo, Sachin A. Ingale, Haozhe Yang, Yang He, Frank Seela, Org. Biomol. Chem., 2017, 15, 870.
555. Enzymatic Synthesis and Phosphorolysis of 4(2)-Thioxo- and 6-Azapyrimidine Nucleosides by E. coli Nucleoside Phosphorylases
Vladimir A. Stepchenko, Anatoly I. Miroshnikov, Frank Seela, Igor A. Mikhailopulo, Beilstein J. Org. Chem., 2016, 12, 2588.
554. "Bis-Click" Ligation of DNA: Template-Controlled Assembly, Circularization and Functionalization with Bifunctional and Trifunctional Azides
Haozhe Yang, Frank Seela, Chem. Eur. J., 2017, 23, 3375.
553. Using NMR and Molecular Dynamics to Link Structure and Dynamics Effects of the Universal Base 8-aza, 7-deaza, N8 linked Adenosine Analog
Spring, Alexander; Evich, Marina; Debelak, Harald; Seela, Frank; Germann, Markus W., Nucleic Acids Res., 2016, doi:1093/nar/gkw736.
552. 7-Deaza-2’-deoxyguanosine: Selective Nucleobase Halogenation, Positional Impact of Space-Occupying Substituents and Stability of DNA with Parallel and Antiparallel Strand Orientation
S. Ingale, F. Seela, J. Org. Chem., 2016, 81, 8331.
551. Silver Ions in Non-Canonical DNA Base Pairs: Metal-Mediated Mismatch Stabilization of 2’-Deoxyadenosine and 7-Deazapurine Derivatives with 2'-Deoxycytidine and 2'-Deoxyguanosine
H. Yang, F. Seela, Chem. Eur. J., 2016, 22, 13336.
550. 2’-O-Methyl- and 2’-O-Propargyl-5-methylisocytidine: Synthesis, Properties and Impact on Nucleic Acid Double Helix Stability
S. K. Jana, P. Leonard, S. A. Ingale, F. Seela, Org. Biomol. Chem., 2016, 14, 4927.
549. Circular DNA by “Bis-Click” Ligation: Template Independent Intramolecular Circularization of Oligonucleotides with Terminal Alkynyl Groups Utilizing Bifunctional Azides
H. Yang, F. Seela, Chem. Eur. J., 2016, 22, 1435.
548. Robust silver-mediated imidazolo-dC base pairs in metal DNA: dinuclear silver bridges with exceptional stability in double helices with parallel and antiparallel strand orientation
S. K. Jana, X. Guo, H. Mei, F. Seela, Chem. Commun., 2015, 51, 17301.
547. DNA with Parallel Strand Orientation: A Nanometer Distance Study with Spin Labels in the Watson-Crick and the Reverse Watson-Crick Double Helix
D. Wunnicke, P. Ding, H. Yang, F. Seela, H.- J. Steinhoff, J. Phys. Chem. B, 2015, 119, 13593.
546. Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase vs its Ser90Ala Mutant in the Synthesis of Base Modified Nucleosides
I. V. Fateev, M. I. Kharitonova, K. V. Antonov, I. D. Konstantinova,V. N. Stepanenko, R. S. Esipov, F. Seela, K. W. Temburnikar, K. L. Seley-Radtke ,V. A. Stepchenko, Y. A. Sokolov, A. I. Miroshnikov, I. A. Mikhailopulo, Chem. Eur. J., 2015, 25, 13401.
545. 3-Phenyl-5,6,7,8-tetrahydropyrimido[4,5-c]pyridazin-7-one as nucleobase substitute in DNA: Synthesis of the 2'-deoxyribonucleoside, cyclonucleoside formation and base pairing in oligonucleotides
H. Mei, S. A. Ingale, F. Seela, Tetrahedron, 2015, 71, 6170.
544. Pyrrolo-dC Metal-Mediated Base Pairs in the Reverse Watson-Crick Double Helix: Enhanced Stability of Parallel DNA and Impact of 6-Pyridinyl Residues on Fluorescence and Silver Ion Binding
H. Yang, H. Mei, F. Seela, Chem. Eur. J., 2015, 21, 10207.
543. Duplex DNA and DNA-RNA Hybrids with Parallel Strand Orientation: 2’-Deoxy-2’-fluoroisocytidine, 2’-Deoxy-2’-fluoroisoguanosine and Canonical Nucleosides with 2’-Fluoro Substituents Cause Unexpected Changes on the Double Helix Stability
S. A. Ingale, P. Leonard, Q. N. Tran, F. Seela, J. Org. Chem., 2015, 80, 3124.
542. 7-Cyclopropyl-2′-deoxytubercidin: a carbocyclic side chain derivative of 7-deaza-2′-deoxyadenosine
H. Yang, S. Budow-Busse, H. Eickmeier, H. Reuter and F. Seela, Acta.Cryst., 2014, C70, 1116.
541. High-Density Functionalization and Cross-linking of DNA: “Click” and “Bis-Click” Cycloadditions Performed on Alkynylated Oligonucleotides with Fluorogenic Anthracene Azides
S. S. Pujari, S. A. Ingale, F. Seela, Bioconjugate Chemistry, 2014, 25, 1855.
540. 5-Nitroindole oligonucleotides with alkynyl side chains: universal base pairing, triple bond hydration and properties of pyrene “click” adducts
S. A. Ingale, P. Leonard, H. Yang, F. Seela, Org. Biomol. Chem., 2014, 12, 8519.
539. Imidazolo-dC Metal-Mediated Base Pairs: Purine Nucleosides Capture Two Ag+ Ions and Form a Duplex with the Stability of a Covalent DNA Cross-Link
H. Mei, S. A. Ingale, F. Seela, Chem. Eur. J., 2014, 20, 16248.
538. The chemoenzymatic synthesis of clofarabine and related 2′-deoxyfluoroarabinosyl nucleosides: the electronic and stereochemical factors determining substrate recognition by E. coli nucleoside phosphorylases
I. V. Fateev, K. V. Antonov, I. D. Konstantinova, T. I. Muravyova, F. Seela, R. S. Esipov, A. I. Miroshnikov, I. A. Mikhailopulo, Beilstein J. Org. Chem., 2014, 10, 1657.
537. Silver Arrays Inside DNA Duplexes Constructed from Ag+-mediated Pyrrolo-dC – Pyrrolo-dC Base Pairs
H. Mei, H.Yang, I. Röhl, F. Seela, ChemPlusChem, 2014, 914.
536. Oligonucleotides with “Clickable” Sugar Residues: Synthesis, Duplex Stability and Terminal versus Central Interstrand Cross-Linking of 2’-O-Propargylated 2-Aminoadenosine with a Bifunctional Azide
S. S. Pujari, P. Leonard and F. Seela, J. Org. Chem., 2014, 79, 4423.
535. Nucleoside and oligonucleotide pyrene conjugates with 1,2,3-triazolyl or ethynyl linkers: synthesis, duplex stability and fluorescence changes generated by the DNA-dye connector
S. A. Ingale, F. Seela, Tetrahedron, 2014, 70, 380.
534. Ethynyl Side Chain Hydration During Synthesis and Work up of “Clickable” Oligonucleotides: Bypassing Acetyl Group Formation by Triisopropylsilyl Protection
S. Ingale, H. Mei, P. Leonard, F. Seela, J. Org. Chem., 2013, 78, 11271.
533. Ag+-mediated DNA base pairing: extraordinary stable pyrrolo-dC – pyrrolo-dC pairs binding two silver ions
Hui Mei, Ingo Röhl and Frank Seela, J. Org. Chem., 2013, 78, 9457.
532. Parallel Stranded DNA Stabilized with Internal Sugar Cross-links: Synthesis and Click Ligation of Oligonucleotides Containing 2’-Propargylated Isoguanosine
S. S. Pujari, F. Seela, J. Org. Chem., 2013, 78, 8545.
531. 1,7-Dideaza-2'-deoxy-6-nitronebularine: a pyrrolo[2,3-b]pyridine nucleoside with an intramolecular hydrogen bond stabilizing the syn conformation
H. Yang, S. Budow, H. Eickmeier, H. Reuter, F. Seela, Acta Cryst., 2013, C69, 892.
530. Pyrene and Bis-Pyrene DNA Nucleobase Conjugates: Excimer and Monomer Fluorescence of Linear and Dendronized Cytosine and 7-Deazaguanine Click Adducts
H. Mei, S. A. Ingale, F. Seela, Tetrahedron, 2013, 69, 4731.
529. Stepwise Click Functionalization of DNA Through a Bifunctional Azide with a Chelating and a Non-chelating Azido Group
S. A. Ingale and F. Seela, J. Org. Chem., 2013, 78, 3394.
528. Construction and Assembly of Chimeric DNA: Oligonucleotide Hybrid Molecules Composed of Parallel or Antiparallel Duplexes and Tetrameric i-Motifs
H. Mei, S. Budow, F. Seela, Biomacromolecules, 2012, 13, 4196.
527. A Ratiometric Fluorescent On-Off Zn2+ Chemosensor Based On a Tripropargylamine Pyrene Azide Click Adduct
S. Ingale, F. Seela, J. Org. Chem., 2012, 77, 9352.
526. 5-Ethynyl-2'-deoxycytidine: a DNA building block with a "clickable" side chain
F. Seela, H. Mei, H. Xiong, S. Budow, H. Eickmeier, H. Reuter, Acta Cryst., 2012, C68, o395.
525. A Nucleobase Discriminating Pyrrolo-dC Click Adduct Designed for DNA Fluorescence Mismatch Sensing
X. Ming, F. Seela, Chem. Eur. J., 2012, 18, 9590.
524. Enzymatic Synthesis of 2ʹ-Deoxy-ß-D-ribonucleosides of 8-Azapurines and 8-Aza-7-deazapurines
V. A. Stepchenko, F. Seela, R. S. Esipov, A. I. Miroshnikov, Y. A. Sokolov, I. A. Mikhailopulo, Synlett, 2012, 10, 1541.
523. Cross-Linked DNA: Propargylated Ribonucleosides as “Click” Ligation Sites for Bifunctional Azides
S.S. Pujari, F. Seela, J. Org. Chem., 2012, 77, 4460.
522. Cross-Linked DNA: Site Selective “Click” Ligation in Duplexes with Bis-Azides and Stability Changes Caused by Internal Cross-Links
H. Xiong, F. Seela, Bioconjugate Chemistry, 2012, 23, 1230.
521. A 2'-deoxycytidine long linker click adduct forming two conformers in the asymmetric unit
F. Seela, H. Xiong, S. Budow, H. Eickmeier, H. Reuter, Acta. Cryst., 2012, C68, o174.
520. Construction and Assembly of Branched Y-shaped DNA: “Click” Chemistry Performed on Dendronized 8-Aza-7-deazaguanine Oligonucleotides
H. Xiong, P. Leonard, F. Seela, Bioconjugate Chemistry, 2012, 23, 856.
519. Site-directed spin labeling of DNA reveals mismatch induced nanometer distance changes of flanking nucleotides
D. Wunnicke, P. Ding, F. Seela, H.-J. Steinhoff, J. Phys. Chem. B, 2012, 116, 4118.
518. 7-Halogenated 7-deazapurine 2′-C-methylribonucleosides
F.Seela, S. Budow, K. Xu, X. Peng, H. Eickmeyer, Collect. Czech. Chem. Commun., 2011, 76, 1413.
517. Parallel-stranded DNA: Enhancing duplex stability by the ‘G-clamp’ and a pyrrolo-dC derivative
X. Ming, P. Ding, P. Leonard, S. Budow, F. Seela, Org. Biomol. Chem., 2012, 10, 1861.
516. 7-Deazapurine and 8-Aza-7-deazapurine Nucleoside and Oligonucleotide Pyrene “Click” Conjugates: Synthesis, Nucleobase Controlled Fluorescence Quenching and Duplex Stability
S. A. Ingale, S. S. Pujari, V. R. Sirivolu, P. Ding, H. Xiong, H. Mei, F. Seela, J. Org. Chem., 2012, 77, 188-198.
515. Hydrogelation and spontaneous fiber formation of 8-aza-7-deazaadenine
nucleoside “click” conjugates
F. Seela, S. S. Pujari, A. H. Schäfer, Tetrahedron, 2011, 67, 7418.
514. Stepwise “Click” Chemistry for the Template Independent Construction of a Broad
Variety of Cross-linked Oligonucleotides: Influence of Linker Length, Position and
Linking Number on DNA Duplex Stability
H. Xiong, F. Seela, J. Org.Chem., 2011, 76, 5584.
513. 7-Deazapurine (Pyrrolo[2,3-d]pyrimidine) 2'-Deoxyribonucleosides: Syntheses and Transformations
F. Seela, S. Budow, X. Peng, Current Organic Chemistry, 2012, 16, 161-223.
512. DNA Gold Nanoparticle Conjugates Incorporating Thiooxonucleosides:
7-Deaza-6-thio-2’-deoxyguanosine as Gold Surface Anchor
F. Seela, P. Ding, S. Budow, Bioconjugate Chemistry, 2011, 22, 794.
511. 1,N6-Etheno-2'-deoxytubercidin hemihydrate
F. Seela, P. Ding, P. Leonard, H. Eickmeier, H. Reuter, Acta Cryst., 2011, C67, o111.
510. Cross-linked DNA Generated by “Bis-click” Reactions with Bis-functional Azides: Site Independent Ligation of Oligonucleotides via Nucleobase Alkynyl Chains
S. S. Pujari, H. Xiong and F. Seela, J. Org. Chem., 2010, 75, 8693.
509. 7-Amino-1-(2-deoxy-β-erythro-pentofuranosyl)-1H-1,2,3- triazolo[4,5-d]pyrimidine: an 8-azaadenine nucleoside with the nucleobase in syn conformation
D. Jiang, Y. He, S. Budow, Z. Kazimierczuk, H. Eickmeier, H. Reuter and F. Seela, Acta Cryst., 2010, C66, o561.
508. Efficient Synthesis of the tRNA Nucleoside PreQ0, 7-Cyano-7-deazaguanosine, via Microwave-assisted Iodo → Carbonitrile Exchange
X. Ming, F. Seela, Chemistry & Biodiversity, 2010, 7, 2616.
507. Spatially Controlled DNA Nano-patterns by “Click” Chemistry Using Oligonucleotides with Different Anchoring Sites
G. Qing, H. Xiong, F. Seela,T. Sun, J. Am. Chem.Soc., 2010, 132, 15228.
506. Site-directed Spin Labeling of DNA by the Azide-Alkyne ‘Click’ Reaction: Nanometer Distance Measurements on 7-Deaza-2’-deoxyadenosine and 2’-Deoxyuridine Nitroxide Conjugates Spatially Separated or Linked to a ‘dA-dT’ Base Pair
P. Ding, D. Wunnicke, H-J. Steinhoff, F. Seela, Chem. Eur. J., 2010, 16, 14385.
505. 2-Azapurine Nucleosides: Synthesis, Properties and Base Pairing of Oligonucleotides
S. Budow, F. Seela, Chemistry & Biodiversity, 2010, 7, 2145.
504. Azide-Alkyne “Click” Conjugation of 8-Aza-7-deazaadenine-DNA: Synthesis, Duplex Stability and Fluorogenic Dye Labelling
F.Seela, S. Pujari, Bioconjugate Chemistry, 2010, 21, 1629.
503. Synthesis and “Double Click” Density Functionalization of 8-Aza-7-deazaguanine DNA Bearing Branched Side Chains with Terminal Triple Bonds
F. Seela, H. Xiong, S. Budow, Tetrahedron, 2010, 3930.
502. Triplexes with 8-Aza-2’-deoxyisoguanosine Replacing Protonated dC: Probing Third Strand Stability with a Fluorescent Nucleobase Targeting Duplex DNA
F. Seela, D. Jiang, S. Budow, ChemBioChem, 2010, 11, 1443.
501. 2-Amino-8-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)imidazo[1,2-a]-1,3,5-triazin-4(8H)-one hydrate, a 2'-deoxyguanosine analogue with an altered Watson-Crick recognition site
D. Jiang, S. Budow, V Glaçon, H. Eickmeier,H. Reuter, Y. He, F. Seela, Acta Cryst., 2010, o197.
500. Oligonucleotide Duplexes and Multi-Strand Assemblies with 8-Aza-2’-deoxyisoguanosine: A Fluorescent isoGd Shape Mimic Expanding the Genetic Alphabet and Forming Ionophores
D. Jiang and F. Seela, J. Am. Chem. Soc., 2010, 132, 4016.
499. “Double Click” Reaction on 7-Deazaguanine DNA: Synthesis and Excimer Fluorescence of Nucleosides and Oligonucleotides with Branched Side Chains Decorated with Proximal Pyrenes
F. Seela, S. Ingale, J. Org. Chem., 2010, 75, 284.
498. 2'-Deoxy-5-propynyluridine: a nucleoside with two conformations in the asymmetric unit
S. Budow, H. Eickmeier, H. Reuter and F. Seela, Acta Cryst., 2009, C65, o645.
497. A toyocamycin analogue with the sugar moiety in syn conformation
F. Seela, S. A. Ingale, P. Leonard, H. Eickmeier, H. Reuter, Acta Cryst., 2009, C65, o431.
496. 8-Aza-2’-deoxyguanosine: Base Pairing, Mismatch Discrimination and Nucleobase Anion Fluorescence Sensing in Single-Stranded and Duplex DNA
F. Seela, D. Jiang, K. Xu, Organic & Biomolecular Chemistry, 2009, 7, 3463.
495. The N1-(2'-deoxyribofuranoside) of 3-iodo-5-nitroindole: a universal nucleoside forming nitro•••iodo interactions
S. Budow, P. Leonard, H. Eickmeier, H. Reuter and F. Seela, Acta Cryst., 2009, C65, o100.
494. Studies on the glycosylation of pyrrolo[2,3-d]pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose: the formation of regioisomers during toyocamycin and 7-deazainosine syntheses
P. Leonard, S. A. Ingale, P. Ding, X. Ming and F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2009, 28, 678.
493. 8-Aza-7-deazaguanine Nucleosides and Oligonucleotides with Octadiynyl Side Chains: Synthesis, Functionalization by the Azide-Alkyne ‘Click’ Reaction and Nucleobase Specific Fluorescence Quenching of Coumarin Dye Conjugates
F. Seela, H. Xiong, P. Leonard and S. Budow, Org. Biomol. Chem., 2009, 7, 1374.
492. Azide-alkyne "click" reaction performed on oligonucleotides with the universal nucleoside 7-octadiynyl-7-deaza-2'-deoxyinosine
X. Ming, P. Leonard, D. Heindl, F. Seela, Nucleic Acids Symp.Ser., 2008, 52, 471.
491. Nucleosides and Oligonucleotides Containing 1,2,3-Triazole Residues with Nucleobase Tethers: Synthesis via the Azide-Alkyne “Click” Reaction”
P. Chittepu, V. R. Sirivolu and F. Seela, Bioorganic and Medicinal Chemistry, 2008, 16, 8427.
490. Substituted benzimidazoles: antiviral activity and synthesis of nucleosides
S. Budow, M. Kozlowska, A. Gorska, Z. Kazimierczuk, H. Eickmeier, P. La Colla, G. Gosselin, F. Seela, Arkivoc, 2009, 225.
489. 7-Deaza-2'-deoxyinosine, a nucleoside showing ambiguous base pairing properties against the four canonical DNA constituents
F. Seela, X. Ming, H. Eickmeier, H. Reuter, Acta Cryst., 2008, C64, o417.
488. 2’-Deoxyimmunosine: Stereoselective Synthesis and Base Pairing of Oligonucleotides Containing 8-Oxo-7-thiaguanine
F. Seela, X. Ming, P. Leonard, Collection Symposium Series, 2008, 10, 142.
487. DNA with Branched Internal Side Chains: Synthesis of 5-Tripropargylamine-dU and Conjugation by an Azide-Alkyne Double Click Reaction
V. R.Sirivolu, P.Chittepu, F. Seela, ChemBioChem, 2008, 9, 2305.
486. DNA with stable fluorinated dA and dG substitutes: syntheses, base pairing and 19F-NMR spectra of 7-fluoro-7-deaza-2’-deoxyadenosine and 7-fluoro-7-deaza-2’-deoxyguanosine
F. Seela, K. Xu, Org. Biomol. Chem., 2008, 6, 3552.
485. 7-Fluorotubercidin: a halogenated derivative of a naturally occurring nucleoside antimetabolite
F. Seela, X. Ming, S. Budow, H. Eickmeier, H. Reuter, Acta Cryst., 2008, C64, o293.
484. Oligonucleotides Containing 7-Deaza-2’-deoxyinosine as Universal Nucleoside: Synthesis of 7-Halogenated and Alkynylated Derivatives, Ambiguous Base Pairing and Dye Functionalization by the Alkyne-Azide “Click”- Reaction
F. Seela, X. Ming, Helv. Chim. Acta, 2008, 91, 1181.
483. 7-Halogenated 7-Deazapurine 2’-Deoxyribonucleosides Related to 2’-Deoxyadenosine, 2’-Deoxyxanthosine and 2’-Deoxyisoguanosine: Syntheses and Properties
F. Seela, K. Xu, Helv. Chim. Acta, 2008, 91, 1083.
482. Mismatch formation in solution and on DNA microarrays: how modified nucleosides can overcome shortcomings of imperfect hybridization caused by oligonucleotide composition and base pairing
F. Seela, S. Budow, Molecular Biosystems, 2008, 4, 232.
481. 2’-Deoxyimmunosine: Stereoselective Synthesis, Base Pairing and Duplex Stability of Oligonucleotides Containing 8-Oxo-7-thiaguanine
F. Seela, X. Ming, Org. Biomol. Chem., 2008, 6, 1450.
480. 6-Azauracil and 8-Aza-7-deazaadenine 2'-Deoxy-2'-fluoroarabinofuranosides: 2’-Fluorine Substituents and Heterocyclic Nitrogens Influence Nucleoside Conformation and Oligonucleotide Duplex Stability
F. Seela, P. Chittepu, Org. Biomol. Chem, 2008, 6, 596.
479. Pyrrolo-dC Oligonucleotides Bearing Alkynyl Side Chains with Terminal Triple Bonds: Synthesis, Base Pairing and Fluorescent Dye Conjugates Prepared by the Azide–Alkyne “Click” Reaction
F. Seela, V. R. Sirivolu, Org. Biomol. Chem., 2008, 6, 1674.
478. Nucleosides and Oligonucleotides with Diynyl Side Chains: The Huisgen-Sharpless Cycloaddition “Click reaction’’ Performed on DNA and their Constituents
F. Seela, V. R. Sirivolu, Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, 597.
477. The Modification of DNA with Octadiynyl Side Chains: Synthesis, Base Pairing and Formation of Fluorescent Coumarin Dye Conjugates of Four Nucleobases by the Alkyne–Azide “Click” Reaction
F. Seela, V. R. Sirivolu and P. Chittepu, Bioconjugate Chemistry, 2008, 19, 211.
476. Symmetrically and Unsymmetrically Bridged Methylidenebis(allopurinols): Synthesis of Dimeric Potential Anti-Gout Drugs
H. Rosemeyer, M. Anders, F. Seela, Molecules, 2007, 12, 563.
475. Oligonucleotides Forming an i-Motif: The pH-Dependent Assembly of Individual Strands and Branched Structures Containing 2’-Deoxy-5-propynylcytidine
F. Seela, S. Budow, P. Leonard, Org. Biomol. Chem., 2007, 5, 1858.
474. pH-Dependent Assembly of DNA-Gold Nanoparticles Based on the i-Motif
F. Seela, S. Budow, Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, 755.
473. Fluorinated 7-Deazapurine 2'-Deoxyribonucleosides: Modification at the Nucleobase and the Sugar Moiety
F. Seela, K. Xu, P. Chittepu, X. Ming, Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, 607.
472. Pyrazolo[3,4-d]pyrimidine ribonucleosides related to 2-aminoadenosine and isoguanosine: synthesis, deamination and tautomerism
F. Seela, K. Xu, Org. Biomol. Chem., 2007, 5, 3034.
471. 2'-Deoxyimmunosine: a thiazolo[4,5-d]pyrimidine nucleoside adopting the syn conformation
F. Seela, X. Ming, S. Budow, H. Eickmeier, H. Reuter, Acta Cryst., 2007, C63, o549–o551.
470. 7-Functionalized 7-deazapurine ß-D and ß-L-ribonucleosides related to tubercidin and 7-deazainosine: glycosylation of pyrrolo[2,3-d]pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-ß-D or ß-L-ribofuranose
F. Seela, Xin Ming, Tetrahedron, 2007, 63, 9850.
469. The 7-bromo derivative of 2-amino-2'-deoxytubercidin fluorinated at the sugar moiety
F. Seela, P. Ding, X. Peng, H. Eickmeier, H. Reuter, Acta Cryst., 2007, C63, o600.
468. Oligonucleotides Containing 6-Aza-2’-deoxyuridine: Synthesis, Nucleobase Protection, pH-Dependent Duplex Stability and Metal-DNA Formation
F. Seela, P.Chittepu, J. Org. Chem., 2007, 72, 4358.
467. An Efficient Synthesis of 7-Functionalized 7-Deazapurine β-D- or β-L-Ribonucleosides: Glycosylation of Pyrrolo[2,3-d]pyrimidines with 1-O-Acetyl-2,3,5-tri-O-benzoyl-D- or L-Ribofuranose
X. Peng, F. Seela, Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, 603.
466. Mismatch Discrimination of Base-Modified Nucleic Acids and their Constituents: Non-Watson-Crick Base Pairing Induced by Tautomerization
F. Seela, X. Peng, K. Xu, Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, 1569.
465. 7-Deaza-2’-deoxyxanthosine: Nucleobase-Protection and Base Pairing of Oligonucleotides
K.I. Shaikh, P. Leonard and F. Seela, Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, 737.
464. 6-Aza-2'-deoxyuridine and N(3)-anisoyl-6-aza-2'-deoxyuridine
F. Seela, P. Chittepu. Y. He, H. Eickmeier, H. Reuter, Acta Cryst. C62, 2007, 0173.
463. Association temperature governs structure and apparent thermodynamics
of DNA–gold nanoparticles
B. Beermann, E. Carillo-Nava, A. Scheffer, W. Buscher, A. M. Jawalekar, F. Seela, H.-J. Hinz, Biophysical Chemistry, 2007, 126, 124.
462. Nucleosides and Oligonucleotides with Diynyl Side Chains: Base Pairing and Functionalization of 2'-Deoxyuridine Derivatives by the CuI-Catalyzed Alkyne-Azide “Click’’ Cycloaddition
F. Seela, V. R. Sirivolu, Helv. Chim. Acta, 2007, 90, 535.
461. 2'-Deoxy-2-fluorotubercidin
F. Seela, X. Peng, H. Eickmeier, H. Reuter, Acta Cryts., 2007, C63, 096.
460. 2'-Deoxy-5-propynylcytidine: a nucleoside forming two solid state conformations
F. Seela, S. Budow, H. Eickmeier, H. Reuter, Acta Cryst., 2007, C63, 054.
459. 1,N6 -Etheno-2’-deoxytubercidin and pyrrolo-C: Synthesis, base pairing and fluorescence properties of 7-deazapurine nucleosides and oligonucleotides
F.Seela, E. Schweinberger, K. Xu, V. Ramana Sirivolu, H. Rosemeyer, E.M. Becker, Tetrahedron, 2007, 63, 3471.
458. Advances in the Synthesis of 7-Deazapurine - Pyrrolo[2,3-d]pyrimidine - 2’-Deoxyribonucleosides Including D-and L-Enantiomers, Fluoro Derivatives and 2',3'-Dideoxyribonucleosides
F. Seela, X. Peng, S. Budow, Current Organic Chemistry, 2007, 11, 427.
457. pH-Dependent mismatch discrimination of oligonucleotide duplexes containing 2'-deoxytubercidin and 2- or 7-substituted derivatives: protonated base pairs formed between 7-deazapurines and cytosine
X. Peng, H. Li, F. Seela, Nucleic Acids Res., 2006, 5987.
456. pH-Dependent Assembly of DNA-Gold Nanoparticles Based on the i-Motif: A Switchable Device with the Potential of a Nanomachine
F. Seela, S. Budow, Helv. Chim. Acta, 2006, 89, 1978.
455. 2-Amino-7-chloro-2'-deoxytubercidin
F. Seela, X. Peng, H. Eickmeier, H. Reuter, Acta Cryst., 2006, C62, 593.
454. Pyrrolo[2,3-d]pyrimidine β-L-Nucleosides Containing 7-Deazaadenine, 2-Amino-7-deazaadenine, 7-Deazaguanine, 7-Deazaisoguanine, and 7-Deazaxanthine
F. Seela, X. Peng, Collect. Czech. Chem. Commun., 2006, 71, 956.
453. Oligonucleotides Containing 7-Deaza-2’-deoxyxanthosine: Synthesis, Base-Protection and Base Pair Stability
F. Seela, K. I. Shaikh, Helv. Chim. Acta, 2006, 89, 2794.
452. 7-Deaza-2,8-diazaadenosine
W. Lin, X. Ming, H. Eickmeier, F. Seela, Acta Cryst., 2006, C62, 0379.
451. DNA Containing Side Chains with Terminal Triple Bonds: Base Pair Stability and Functionalization of Alkynylated Pyrimidines and 7-Deazapurines
F. Seela, V. Ramana Sirivolu, Chemistry & Biodiversity, 2006, 3, 509.
450. pH-Independent triplex formation: hairpin DNA containing isoguanine or
9-deaza-9-propynylguanine in place of protonated cytosine
F. Seela, K. I. Shaikh, Org. Biomol. Chem., 2006, 4, 3993.
449. 2'-Deoxy-7-propynyl-7-deazaadenosine: a duplex-stabilizing nucleoside
F. Seela, K. I. Shaikh, S. Budow, H. Eickmeier, Acta Cryst., 2006, C62, 0246.
448. Fluorinated Pyrrolo[2,3-d]pyrimidine Nucleosides: 7- Fluoro-7-deazapurine 2’-Deoxyribofuranosides and 2'-Deoxy-2’-fluoroarabinofuranosyl Derivatives
F. Seela, K. Xu, P. Chittepu, Synthesis, 2006, 2005.
447. 4-Amino-7-(2-deoxy-2-fluoro-ß-D-arabinofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine: a bis-fluorinated analogue of 2'-deoxytubercidin
F. Seela, P. Chittepu, H. Eickmeier, Acta Cryst., 2006, C62, 0231.
446. Progress in 7-Deazapurine - Pyrrolo[2,3-d]pyrimidine - Ribonucleoside Synthesis
F. Seela, X. Peng, Curr. Top. Med. Chem., 2006, 6, 867.
445. Binding of Actinomycin C1 (D) and Actinomin to Base-Modified Oligonucleotide Duplexes with Parallel Chain Orientation
H. Li, X. Peng, P. Leonard, F. Seela, Bioorg. Med. Chem., 2006, 14, 4089.
444. pH-Independent Recognition of the dG-dC Base Pair in Triplex DNA: 9-Deazaguanine N7-(2’-Deoxyribonucleoside) and Halogenated Derivatives Replacing Protonated dC
F. Seela, K. I. Shaikh, T. Wiglenda, Helv. Chim. Acta, 2006, 598.
443. 7-Functionalized 7-Deazapurine Ribonucleosides Related to 2-Aminoadenosine, Guanosine, and Xanthosine: Glycosylation of Pyrrolo[2,3-d]pyrimidines with 1-O-Acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose
F. Seela, X. Peng, J. Org. Chem., 2006, 71, 81.
442. N8-(2'-O-Methylribofuranosyl)-8-aza-7-deazaadenine monohydrate
X. Zhang, S. Budow, P. Leonard, H. Eickmeier, F. Seela, Acta Cryst., 2006, C 62, 79-81.
441. 8-Aza-7-deaza-2'-deoxy-2-(methylsulfanyl)adenosine
F. Seela, A. M. Jawalekar, S. Budow, H. Eickmeier, Acta Cryst., 2005, C61, o562.
440. 2'-Deoxy-5-fluorotubercidin
F. Seela, K. Xu, H. Eickmeier, Acta Cryst., 2005, C61, o408.
439. Stabilization of tandem dG-dA base pairs in DNA-hairpins: replacement of the canonical bases by 7-deaza-7-propynylpurines
F. Seela, S. Budow, K. I. Shaikh, A. Jawalekar, Org. Biomol. Chem., 2005, 3, 4221.
438. Oligonucleotides containing pyrazolo[3,4-d]pyrimidines: 8-aza-7-deazaadenines with bulky substituents in the 2- or 7-position
F. Seela, A. M. Jawalekar, L. Sun, P. Leonard, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 1485.
437. 7-Deaza-2,8-diazaadenine containing oligonucleotides: synthesis, ring opening and base pairing of 7-halogenated nucleosides
W. Lin, K. Xu, F. Seela, Tetrahedron, 2005, 61, 7520.
436. 1,N6-Etheno-7-deaza-2,8-diazaadenosine: Syntheses, properties and conversion to 7-deaza-2,8-diazaadenosine
W. Lin, H. Li, X. Ming, F. Seela, Org. Biomol. Chem., 2005, 3, 1714.
435. Base-pairing, Tautomerism, and Mismatch Discrimination of 7-Halogenated 7-Deaza-2'-deoxyisoguanosine: Oligonucleotide Duplexes with Parallel and Antiparallel Chain Orientation
F. Seela, X. Peng, H. Li, J. Am. Chem. Soc., 2005, 127, 7739.
434. 8-Aza-7-deaza-7-propynyladenosine methanol solvate
W. Lin, K. Xu, H. Eickmeier, F. Seela, Acta Cryst., 2005, C61, o195.
433. 7-Deaza-2'-deoxyguanosine
F. Seela, K. I. Shaikh, H. Eickmeier, Acta Cryst., 2005, C61, o151.
432. Replacement of Canonical DNA Nucleobases by Benzotriazole and 1,2,3-Triazolo[4,5-d]pyrimidine: Synthesis, Fluorescence, and Ambiguous Base Pairing
F. Seela, A. M. Jawalekar, I. Münster, Helv. Chim. Acta, 2005, 88, 751.
431. Parallel and Antiparallel DNA: Fluorescence Quenching of Ethidium Bromide by 7-Deazapurines
H. Li, F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 865.
430. Propynyl Groups in Duplex, Hairpin and Triplex DNA: Substituted 7-Deazapurines and 9-Deazapurines
F. Seela, K. I. Shaikh, S. Budow, A. M. Jawalekar, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 851.
429. L-Nucleosides Containing Modified Nucleobases
F. Seela, W. Lin, Z. Kazimierczuk, H. Rosemeyer, V. Glacon, X. Peng, Y. He, X. Ming, M. Andrzejewska, A. Gorska, X. Zhang, H. Eickmeier, P. La Colla, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 859.
428. 7-Deazapurin-2,6-Diamine and 7-Deazaguanine: Synthesis and Property of 7-Substituted Nucleosides and Oligonucleotides
F. Seela, X. Peng, X. Ming, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 869.
427. 7-Substituted 8-Aza-7-Deazapurines and 2,8-Diaza-7-Deaza-Purines: Synthesis of Nucleosides and Oligonucleotides
W. Lin, K. Xu, F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 869.
426. 6-Azapyrimidine and 7-Deazapurine 2'-Deoxy-2'-Fluoroarabinonucleosides: Synthesis, Conformation and Properties of Oligonucleotides
F. Seela, P. Chittepu, Y. He, J. He, K. Xu, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 847.
425. Comparative Conformational Analysis of Nucleosides by NMR, X-Ray, and Semi-empirical (PM3 vs AM1) Methods
I. A. Mikhailopulo, Y. A. Sokolov, J. He, P. Chittepu, H. Rosemeyer, F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 701.
424. Gold DNA-Conjugates: Ion Specific Self-Assembly of Gold Nanoparticles via the dG-Quartet
F. Seela, A. M. Jawalekar, L. Chi, D. Zhong, H. Fuchs, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 843.
423. Novel DNA Nanoparticles and Networks
F. Seela, A. M. Jawalekar, V. R. Sirivolu, H. Rosemeyer, Y. He, P. Leonard, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 855.
422. Synthesis of 5-Aza-7-Deazaguanine Nucleoside Derivatives as Potential Anti-Flavivirus Agents
D. Dukhan, F. Leroy, J. Peyronnet, E. Bosc, D. Chaves, M. Durka, R. Storer, P. La Colla, Nucleosides, Nucleotides & Nucleic Acids, 2005, 24, 671.
421. Oligonucleotides containing 7-propynyl-7-deazaguanine: synthesis and base pair stability
F. Seela, K. I. Shaikh, Tetrahedron, 2005, 61, 2675.
420. 7-Vinyl-8-aza-7-deaza-2'-deoxyadenosine monohydrate
F. Seela, Y. Zhang, K. Xu, H. Eickmeier, Acta Cryst., 2005, C61, o60.
419. Ion-Specific Aggreagation of Gold-DNA Nanoparticles Using the dG-Quartet Hairpin 5'-d(G4T4G4)
F. Seela, A. M. Jawalekar, L. Chi, D. Zhong, Chemistry & Biodiversity, 2005, 2, 84.
418. Universal Bases: Base Pairing and Duplex Stability of Oligonucleotides Containing Pyrrolo[2,3-d]pyrimidines and 5-Nitroindole Nucleosides
P. Leonard, X. Ming, A. M. Jawalekar, W. Thür, D. Heindl, F. Seela, Collection Symposium Series, 2005, 7, 429.
417. 3-Bromo-1-(2-deoxy-β-D-erythropentofuranosyl)-1H-pyrazolo[3,4-d]pyrimidin-4,6-diamine: a nucleoside which strongly enhances DNA duplex stability
F. Seela, V. R. Sirivolu, J. He, H. Eickmeier, Acta Cryst., 2005, C61, o67.
416. Base-modified oligodeoxyribonucleotides: Pyrrolo[2,3-d]pyrimidines replacing purines
F. Seela, X. Peng, in 'Current Protocols in Nucleic Acid Chemistry', Eds. S. L. Beaucage, D. E. Bergstrom, G. D. Glick, R. A. Jones, John Wiley & Sons, 2005.
415. Pyrrolo[2,3-d]pyrimidines: Synthesis and properties of 2'-deoxyribonucleosides
F. Seela, X. Peng, in 'Current Protocols in Nucleic Acid Chemistry', Eds. S. L. Beaucage, D. E. Bergstrom, G. D. Glick, R. A. Jones, John Wiley & Sons, 2005.
414. Modified DNA: from synthesis to molecular recognition
F. Seela, X. Peng, H. Li, P. Chittepu, K. I. Shaikh, J. He, Y. He, I. Mikhailopulo, Collection Symposium Series, 2005, 7, 1.
413. 6-Aza-2'-deoxy-2'-arabinofluorouridine, a 2'-deoxyribonucleoside with an N-sugar conformation in the solid state and in solution
F. Seela, P. Chittepu, J. He, H. Eickmeier, Acta Cryst., 2004, C60, o884.
412. Fluorescence Quenching of Parallel-stranded DNA Bound Ethidium Bromide: The Effect of 7-Deaza-2'-deoxyisoguanosine and 7-Halogenated Derivatives
H. Li, X. Peng, F. Seela, Bioorg. Med. Chem. Lett., 2004, 14, 6031.
411. Synthesis of the 9-Halogenated 9-Deazaguanine N7-(2'-Deoxyribonucleosides)
F. Seela, K. I. Shaikh, T. Wiglenda, P. Leonard, Helv. Chim. Acta, 2004, 87, 2507.
410. 1,N6-Etheno derivative of 7-deaza-2,8-diazaadenosine
W. Lin, F. Seela, H. Eickmeier, H. Reuter, Acta Cryst., 2004, C60, o556.
409. 7-Iodo-5-aza-7-deazaguanine: Syntheses of Anomeric D- and L-Configured 2-Deoxyribonucleosides
W. Lin, X. Zhang, F. Seela, Helv. Chim. Acta, 2004, 87, 2235.
408. Halogenated 7-deazapurine nucleosides: stereoselective synthesis and conformation of 2'-deoxy-2'-fluoro-β-D-arabinonucleosides
X. Peng, F. Seela, Org. Biomol. Chem., 2004, 2, 2838.
407. 7-Deaza-2'-deoxy-7-propynylguanosine
F. Seela, K. Shaikh, H. Eickmeier, Acta Cryst., 2004, C60, o489.
406. Pyrazolo[3,4-d][1,2,3]triazine DNA: Synthesis and Base Pairing of 7-Deaza-2,8-diaza-2’-deoxyadenosine
F. Seela, M. Lindner, V. Glaçon, W. Lin, J. Org. Chem., 2004, 69, 4695.
405. 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-nitro-1H-indazole
F. Seela, A. M. Jawalekar, H. Eickmeier, Acta Cryst., 2004, C60, o387.
404. Regioselective Syntheses of 7-Halogenated 7-Deazapurine Nucleosides Related to 2-Amino-7-deaza-2'-deoxyadenosine and 7-Deaza-2'-deoxyisoguanosine
F. Seela, X. Peng, Synthesis, 2004, 1203.
403. 7-Halogenated 7-Deaza-2’-deoxyxanthine 2’-Deoxyribonucleosides
F. Seela, K. Shaikh, Helv. Chim. Acta, 2004, 87, 1325.
402. ‘PURINES’
F. Seela, N. Ramzaeva, H. Rosemeyer, in ‘Science of Synthesis’, Vol. 16, 2003, pp. 945-1108.
401. 2-Amino-8-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)imidazo[1,2-a]-1,3,5-triazin-4(8H)-one: Synthesis and Conformation of a 5-Aza-7-deazaguanine Fluoronucleoside
V. Glacon, F. Seela, Helv. Chim. Acta, 2004, 87, 1239.
400. 3-Deazaadenosine analogues of p5'A2'p5'A2'p5'A: synthesis, stereochemistry, and the roles of adenine ring nitrogen-3 in the interaction with RNase L
E. N. Kalinichenko, T. L. Podkopaeva, E. V. Budko, F. Seela, B. Dong, R. Silverman, J. Vepsäläinen, P. F. Torrence, I. A. Mikhailopulo, Bioorg. Med. Chem., 2004, 12, 3637.
399. Single-stranded DNA: Replacement of Canonical by Base-Modified Nucleosides in the Minihairpin 5’-d(GCGAAGC) and Constructs with the Aptamer 5’-d(GGTTGGTGTGGTTGG)-3’
H. Rosemeyer, V. Mokrosch, A. Jawalekar, E.-M. Becker, F. Seela, Helv. Chim. Acta, 2004, 87, 536.
398. Regioselective Synthesis of Indazole N1- and N2-(β-D-Ribonucleosides)
F. Seela, X. Peng, Nucleosides, Nucleotides and Nucleic Acids, 2004, 23, 227.
397. Regioisomeric 4-nitroindazole N1- and N2-(β-D-ribonucleosides)
F. Seela, X. Peng, H. Eickmeier, H. Reuter, Acta Cryst., 2004, C60, o94.
396. Base-modified oligonucleotides with increased duplex stability: pyrazolo[3,4-d]pyrimidines replacing purines
F. Seela, Y. He, J. He, G. Becher, R. Kröschel, M. Zulauf, P. Leonard, in 'Methods in Molecular Biology", in 'Oligonucleotide Synthesis: Methods and Applications', Ed. P. Herdewijn, Humana Press Inc., 2004, vol. 288, pp. 165-186.
395. The Human Telomeric Sequence (T2AG3)n is Efficiently Cross-Linked by AN1 Binding to the Platinum of a trans-Pt(NH3)2 Chelate of an Antisense Oligo-2’-O-Methylribonucleotide
S. Perrier, F. Seela, A. Schwartz, M.Leng, J.-C. Chottard, Eur. J. Inorg. Chem., 2003, 1641.
394. The Base Pairing Properties of 8-Aza-7-deaza-2’-deoxyisoguanosine and 7-Halogenated Derivatives in Oligonucleotide Duplexes with Parallel and Antiparallel Chain Orientation
F. Seela, R. Kröschel, Nucleic Acids Res., 2003, 31, 7150.
393. Oligonucleotide duplexes containing N8-glycosylated 8-aza-7-deazaguanine and the self-assembly of 8-aza-7-deazapurines on the nucleoside and the oligomeric level
F. Seela, R. Kröschel, Org. Biomol. Chem., 2003, 1, 3900.
392. 6-Amino-3-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one-acetone-water (1/1/1): a fluorinated 2’-deoxyguanosine analogue with the sugar conformation of a ribonucleoside
J. He, H. Eickmeier, H. Reuter, F. Seela, Acta Cryst., 2003, C59, o406.
391. 5-Methyl-6-aza-2’-deoxyisocytidine
F. Seela, Y. He, H. Eickmeier, Acta Cryst., 2003, C59, o194.
390. Oligonucleotides incorporating 8-aza-7-deazapurines: synthesis and base pairing of nucleosides with nitrogen-8 as glycosylation position
J. He, F. Seela, Org. Biomol. Chem., 2003, 1, 1873.
389. 3-Bromopyrazolo[3,4-d]pyrimidine 2-deoxy-2-fluoro-β-D-arabinonucleosides: Modified DNA constituents with an unusually rigid sugar N-conformation
J. He, I. Mikhailopulo, F. Seela, J. Org. Chem., 2003, 68, 5519.
388. Synthesis and Enzymic Hydrolysis of Oligoribonucleotides Incorporating 3-Deazaguanosine: The Importance of Nitrogen-3 Atom of Single Conserved Guanosine Residues on the Catalytic Activity of the Hammerhead Ribozyme
F. Seela, H. Debelak, L. Andrews, L. Beigelman, Helv. Chim. Acta, 2003, 86, 2726.
387. 6-Aza-2’-deoxyisocytidine: Synthesis, Properties of Oligonucleotides, and Base-Pair Stability Adjustment of DNA with Parallel Strand Orientation
F. Seela, Y. He, J. Org. Chem., 2003, 68, 367.
386. Propynyl groups in duplex DNA: stability of base pairs incorporating 7-substituted 8-aza-7-deazapurines or 5-substituted pyrimidines
J. He, F. Seela, Nucleic Acids Res., 2002, 30, 5485.
385. Pyrazolo[3,4-d]pyrimidine nucleic acids: Adjustment of the dA-dT to the dG-dC base pair stability
J. He, G. Becher, S. Budow, F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2003, 22, 573.
384. Synthesis and properties of halogenated 7-deaza-2’-deoxyxanthosine and protected derivatives for oligonucleotide synthesis
F. Seela, K. I. Shaikh, T. Wiglenda, Nucleosides, Nucleotides & Nucleic Acids, 2003, 22, 1239.
383. Oligonucleotides incorporating N7-(2’-deoxy-β-D-erythro-pentofuranosyl)isoguanine
P. Leonard, R. Kröschel, F. Seela, Nucleotides, Nucleosides & Nucleic Acids, 2003, 22, 1235.
382. Oligonucleotides incorporating 7-(Aminoalkynyl-1-yl)-7-deaza-2’-deoxyguanosines: Duplex Stability and Phosphodiester Hydrolysis by Exonucleases
H. Rosemeyer, N. Ramzaeva, E.-M. Becker, E. Feiling, F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2003, 22, 1231.
381. Base-modified nucleosides and oligonucleotides: synthesis and application
F. Seela, Collection Symposium Series, 2002, 5, 1.
380. 8-Aza-7-deazaguanine N8-(2’-deoxy-β-D-ribonucleoside): synthesis and base paring
F. Seela, R. Kröschel, Collection Symposium Series, 2002, 5, 361.
379. Oligonucleotides incorporating 6-aza-2’-deoxyisocytidine: harmonization of the base pair stability in parallel DNA and exonuclease resistance
F. Seela, Y. He, Collection Symposium Series, 2002, 5, 319.
378. 4-Nitroindazole: Its ambiguous nature in oligonucleotide base pairing and the influence of the glycosylation position on the duplex stability
F. Seela, A. M. Jawalekar, Collection Symposium Series, 2002, 5, 338.
377. The regioisomeric 1H(2H)--pyrazolo[3,4-d]pyrimidine N1-and N2-(2’-deoxy-β-D-ribofuranosides)
J. He, F. Seela, H. Eickmeier, H. Reuter, Acta Cryst., 2002, C58, 593.
376. 4-Nitroindazole: Its Ambiguous Nature in Oligonucleotide Base Pairing and the Influence of the Glycosylation Position on the Duplex Stability
F. Seela, A. Jawalekar, Helv. Chim. Acta, 2002, 85, 1857.
375. Oligonucleotides Incorporating 7-(Aminoalkynyl)-7-deaza-2’-deoxyguanosines: Duplex Stability and Phosphodiester Hydrolysis by Exonucleases
H. Rosemeyer, N. Ramzaeva, E.-M. Becker, E. Feiling, F. Seela, Bioconjugate Chem., 2002, 13, 1274.
374. ‘5-Aza-7-deazapurines: synthesis and properties of nucleosides and oligonucleotides’
F. Seela, H. Rosemeyer, in ‘Recent Advances in Nucleosides: Chemistry and Chemotherapy’, Ed. C. K. Chu, Elsevier Science B. V., Amsterdam, 2002, p. 505.
373. The α-D anomer of 5-aza-7-deaza-2’-deoxyguanosine
F. Seela, H. Rosemeyer, A. Melenewski, E.-M. Heithoff, H. Eickmeier, H. Reuter, Acta Cryst., 2002, C58, 142.
372. 8-Aza-7-deazapurine–pyrimidine base pairs: the contribution of 2- and 7-substituents to the stability of duplex DNA
J. He, F. Seela, Tetrahedron, 2002, 58, 4535.
371. Modified purine nucleosides as dangling ends of DNA duplexes: The effect of the nucleobase polarizability on stacking interactions
H. Rosemeyer, F. Seela, J. Chem. Soc., Perkin Trans. 2, 2002, 746.
370. Parallel DNA: The application of base-modified nucleosides to control the chain orientation
F. Seela, Y. He, in “Modified Nucleosides, Synthesis and Applications”, in ‘Organic and Bioorganic Chemistry’, Ed. D. Loakes, Transworld Research Network, 2002, pp. 57-85.
369. Base Pairing of 8-Aza-7-deazapurine-2,6-diamine Linked via the N(8)-Position to the DNA-Backbone: Universal Base-Pairing Properties and Formation of Highly Stable Duplexes when Alternating with dT
J. He, F. Seela, Helv. Chim. Acta, 2002, 85, 1340.
368. 7-Deaza-2’-deoxyxanthosine Dihydrate Forms Water-Filled Nanotubes with C-H˙˙˙O Hydrogen Bonds
F. Seela, T. Wiglenda, H. Rosemeyer, H. Eickmeier, H. Reuter, Angew. Chem. Int. Ed., 2002, 41, 603.
367. The Thermal N9/N7 Isomerization of N2-Acylated 2’-Deoxyguanosine Derivatives in the Melt and in Solution
B. Golankiewicz, T. Ostrowski, P. Leonard, F. Seela, Helv. Chim. Acta, 2002, 85, 388.
366. α-Homo-DNA and RNA Form a Parallel Oriented Non-A, Non-B-Type Double Helical Structure
M. Froeyen, E. Lescrinier, L. Kerremans, H. Rosemeyer, F. Seela, B. Verbeure, I. Lagoja, J. Rozenski, A. Van Aerschot, R. Busson, P. Herdewijn, Chem.-Eur. J., 2001, 7, 5183.
365. Quadruplex and Pentaplex Self-Assemblies of Oligonucleotides Containing Short Runs of 8-Aza-7-deaza-2’-deoxyisoguanosine or 2’-Deoxyisoguanosine
F. Seela, R. Kröschel, Bioconjugate Chem., 2001, 12, 1043.
364. 5-Aza-7-deazaguanine DNA: Recognition and Strand Orientation of Oligonucleotides Incorporating Anomeric Imidazo [1,2-a]-1,3,5-triazine Nucleosides
F. Seela, S. Amberg, A. Melenewski, H. Rosemeyer, Helv. Chim. Acta, 2001, 84, 1996.
363. Fluorescent DNA: the development of 7-deazapurine nucleoside triphosphates applicable for sequencing at the single molecule level
F. Seela, E. Feiling, J. Gross, F. Hillenkamp, N. Ramzaeva, H. Rosemeyer, M. Zulauf, Journal of Biotechnology, 2001, 86, 269.
362. Major-Groove-Halogenated DNA: The Effects of Bromo and Iodo Substituents Replacing H-C(7) of 8-Aza-7-deazapurine-2
6-diamine or H-C(5) of Uracil Residues, G. Becher, J. He, F. Seela, Helv. Chim. Acta, 2001, 84, 1048.
361. Pyrazolo[3,4-d]pyrimidine nucleic acids: adjustment of dA-dT to dG-dC base pair stability
F. Seela, G. Becher, Nucleic Acids Res., 2001, 29, 2069.
360. The high-anti conformation of 8-aza-1,3-dideaza-2’-deoxyadenosine
F. Seela, Y. He, H. Reuter, E.-M. Heithoff, Acta Cryst., 2001, C57, 660.
359. The C8-(2’-Deoxy-β-D-ribofuranoside) of 7-Deazaguanine: Synthesis and Base Pairing of Oligonucleotides with Unusually Linked Nucleobases
F. Seela, H. Debelak, J. Org. Chem., 2001, 66, 3303.
358. Phosphoramidites and Oligonucleotides Containing 7-Deazapurines and Pyrimidines Carrying Aminopropargyl side Chains
F. Seela, N. Ramzaeva, P. Leonard, Y. Chen, H. Debelak, E. Feiling, R. Kröschel, M. Zulauf, T. Wenzel, T. Fröhlich, M. Kostrzewa, Nucleosides, Nucleotides & Nucleic Acids, 2001, 20, 1421.
357. Parallel DNA Containing Pyrazolo[3,4-d]pyrimidine Analogues of Isoguanine
F. Seela, R. Kröschel, Y. He, Nucleosides, Nucleotides & Nucleic Acids, 2001, 20, 1283.
356. Cyclohexene Nucleic Acids (CeNA) Form Stable Duplexes with RNA and Induce RNase H Activity
J. Wang, B. Verbeure, I. Luyten, M. Froeyen, C. Hendrix, H. Rosemeyer, F. Seela, A. Van Aerschot, P. Herdewijn, Nucleosides, Nucleotides and Nucleic Acids, 2001, 20, 785.
355. 8-Aza-7-deazaadenine and 7-Deazaguanine: Synthesis and Properties of Nucleosides and Oligonucleotides with Nucleobases linked at Position-8
F. Seela, H. Debelak, Nucleosides, Nucleotides & Nucleic Acids, 2001, 20, 577.
354. Synthesis and base pairing properties of 9-deazaguanine N7-nucleosides in oligonucleotide duplexes and triplexes
P. Leonard, T. Wiglenda, F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2001, 20, 1279.
353. Cyclohexene Nucleic Acids (CeNA): Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA
J. Wang, B. Verbeure, I. Luyten, E. Lescrinier, M. Froeyen, C. Hendrix, H. Rosemeyer, F. Seela, A. Van Aerschot, P. Herdewijn, J. Am. Chem. Soc., 2000, 122, 8595.
352. Pyrophosphoryl Derivatives of 1-(2-Deoxy-3-O-phosphonomethyl-β- and α-D-erythro-pentofuranosyl)thymine: Synthesis and Substrate Properties Towards Some DNA Polymerases‡
I.A. Mikhailopulo, T.I. Kulak, O.V. Tkachenko, S.L. Sentyureva, L.S. Victorova, H. Rosemeyer, F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2000, 19, 1885.
351. The N8-(2’-deoxyribofuranoside) of 8-aza-7-deazaadenine: a universal nucleoside forming specific hydrogen bonds with the four canonical DNA constituents
F. Seela, H. Debelak, Nucleic Acids Res., 2000, 28, 3224.
350. 2’-Deoxyuridine and 2’-Deoxyisocytidine as Constituents of DNA with Parallel Chain Orientation: The Stabilization of the iCd-Gd Base Pair by the 5-Methyl Group
F. Seela, Y. He, Helv. Chim. Acta, 2000, 83, 2527.
349. Pyrrolo[2,3-d]Pyrimidine Nucleosides: Synthesis and Antitumor Activity of 7-Substituted 7-Deaza-2’-Deoxyadenosines
F. Seela, M. Zulauf, S.-F. Chen, Nucleosides, Nucleotides & Nucleic Acids, 2000, 19, 237.
348. Base Pairing Properties of 8-Aza-7-deazaadenine Linked via the 8-Position to the DNA Backbone
F. Seela, M. Zulauf, H. Debelak, Helv. Chim. Acta, 2000, 83, 1437.
347. 2’-Deoxy-5-methylisocytidine
F. Seela, Y. He, H. Reuter, E.-M. Heithoff, Acta Cryst., 2000, C56, 989.
346. 7-Iodo-8-aza-7-deaza-2’-deoxyadenosine and 7-bromo-8-aza-7-deaza-2’-deoxyadenosine
F. Seela, M. Zulauf, H. Reuter, G. Kastner, Acta Cryst., 2000, C56, 489.
345. Fluorescence Properties and Base Pair Stability of Oligonucleotides Containing 8-Aza-7-deaza-2’-deoxyisoinosine or 2’-Deoxyisoinosine
F. Seela, G. Becher, Y. Chen, Nucleosides, Nucleotides & Nucleic Acids, 2000, 19, 1581.
344. Oligonucleotides Functionalized by Fluorescein and Rhodamine Dyes: Michael Addition of Methyl Acrylate to 2’-Deoxy-pseudouridine
N. Ramzaeva, H. Rosemeyer, P. Leonard, K. Mühlegger, F. Bergmann, H. von der Eltz, F. Seela, Helv. Chim. Acta, 2000, 83, 1108.
343. 7-Substituted 7-Deaza-2’-deoxyadenosines and 8-Aza-7-deaza-2’-deoxyadenosines: Fluorescence of DNA Base Analogues Induced by the 7-Alkynyl Side Chain
F. Seela, M. Zulauf, M. Sauer, M. Deimel, Helv. Chim. Acta, 2000, 83, 910.
342. Synthesis, Base Pairing, and Fluorescence Properties of Oligonucleotides Containing 1H-Pyrazolo[3,4-d]pyrimidin-6-amine (8-Aza-7-deazapurin-2-amine) as an Analogue of Purin-2-amine
F. Seela, G. Becher, Helv. Chim. Acta, 2000, 83, 928.
341. The Influence of Modified Purine Bases on the Stability of Parallel DNA
F. Seela, C. Wei, G. Becher, M. Zulauf, P. Leonard, Bioorg. & Med. Chem. Lett., 2000, 10, 289.
340. 2-Aza-2’-deoxyadenosine: Synthesis, Base-Pairing Selectivity, and Stacking Properties of Oligonucleotides
T. Sugiyama, E. Schweinberger, Z. Kazimierczuk, N. Ramzaeva, H. Rosemeyer, F. Seela, Chem. Eur. J., 2000, 6, 369.
339. D-Altritol Nucleic Acids (ANA): Hybridisation Properties, Stability, and Initial Structural Analysis
B. Allart, K. Khan, H. Rosemeyer, G. Schepers, C. Hendrix, K. Rothenbacher, F. Seela, A. Van Aerschot, P. Herdewijn, Chem. Eur. J., 1999, 5, 2424.
338. Synthesis and Pairing Properties of Oligonucleotides Containing 3-Hydroxy-4-hydroxymethyl-1-cyclohexanyl Nucleosides
Y. Maurinsh, H. Rosemeyer, R. Esnouf, A. Medvedovici, J. Wang, G. Ceulemans, E. Lescrinier, C. Hendrix, R. Busson, P. Sandra, F. Seela, A. Van Aerschot, P. Herdewijn, Chem. Eur. J., 1999, 5, 2139.
337. Synthesis and Biological Activity of 2’-Fluoro-D-arabinofuranosylpyrazolo[3,4-d]pyrimidine Nucleosides
A.T. Shortnacy-Fowler, K.N. Tiwari, J. A. Montgomery, R. W. Buckheit, Jr., J. A. Secrist III, F. Seela, Helv. Chim. Acta, 1999, 82, 2240.
336. Oligonucleotides Containing 7-Deazaadenines: The Influence of the 7-Substituent Chain Length and Charge on the Duplex Stability
F. Seela, M. Zulauf, Helv. Chim. Acta, 1999, 82, 1878.
335. Oligonucleotides Containing Pyrazolo[3,4-d] pyrimidines: The Influence of 7-Substituted 8-Aza-7-deaza-2'-deoxyguanosines on the Duplex Structure and Stability
F. Seela, G. Becher, Helv. Chim. Acta, 1999, 82, 1640.
334. The anomers of 8-aza-7-deaza-2'-deoxyadenosine
F. Seela, M. Zulauf, H. Reuter, G. Kastner, Acta Cryst., 1999, C55, 1947.
333. Oligonucleotides Containing the Pyrazolo[3,4-d]pyrimidine Analogue of 2-Aminopurine: Duplexes with Parallel and Antiparallel Chain Orientation
F. Seela, G. Becher, Collection Symp. Ser., 1999, 2, 320.
332. Synthesis, Base Pairing and Stacking Properties of Oligonucleotides Containing 2-Aza-2'-deoxyadenosine
F. Seela, T. Sugiyama, E. Schweinberger, H. Rosemeyer, Collection Symp. Ser., 1999, 2, 124.
331. The Isomerization of 2'-Deoxyguanosine and the Incorporation of Guanine N7-(2'-Deoxy-β-D-ribonucleoside) into Oligonucleotide Duplexes
P. Leonard, T. Ostrowski, B. Golankiewicz, F. Seela, Collection Symp. Ser., 1999, 2, 324.
330. Parallel-Stranded DNA Formed by 1-Deazaadenine, 3-Deazaadenine or 7-Deazaguanine Homo Base Pairs Incorporated in the Duplex of 5'-d[G-A)7-G]
F. Seela, H. Debelak, Collection Symp. Ser., 1999, 2, 316.
329. Parallel-Stranded Oligonucleotide Duplexes Containing 5-Methylisocytosine-Guanine and Isoguanine-Cytosine Base Pairs
F. Seela, Y. He, C. Wei, Tetrahedron, 1999, 55, 9481.
328. 9-(2-Deoxy-α-D-ribofuranosyl)-7-iodo-7-deazaadenine
F. Seela, M. Zulauf, H. Reuter, G. Kastner, Acta Cryst., 1999, C55, 1560.
327. Incorporation of 2'-Deoxysangivamycin in DNA Duplexes: The Conversion of a Pyrrolo[2,3-d]pyrimidine Nitrile to a Carboxamide upon Oligonucleotide Deprotection
F. Seela, M. Zulauf, Nucleosides Nucleotides, 1999, 18, 2697.
326. 7-Deaza-2'-deoxyisoguanosine adopts the form of an N1—H,2-keto tautomer
F. Seela, C. Wei, H. Reuter, G. Kastner, Acta Cryst., 1999, C55, 1335.
325. The Base-Pairing Properties of 7-Deaza-2'-deoxyisoguanosine and 2'-Deoxyisoguanosine in Oligonucleotide Duplexes with Parallel and Antiparallel Chain Orientation
F. Seela, C. Wei, Helv. Chim. Acta, 1999, 82, 726.
324. 7-Deaza-2'-Deoxyguanosines Functionalized with 7-(ω-Aminoalk-1-Ynyl) Residues
N. Ramzaeva, C. Mittelbach, F. Seela, Nucleosides Nucleotides, 1999, 18, 1439.
323. 8-Aza-7-deazapurine DNA: Synthesis and Duplex Stability of Oligonucleotides Containing 7-Substituted Bases
F. Seela, G. Becher, M. Zulauf, Nucleosides Nucleotides, 1999, 18, 1399.
322. Glycerol-Furcated Oligonucleotides: Synthesis and Aggregation
H. Rosemeyer, E. Feiling, W. Nierling, F. Seela, Nucleosides Nucleotides, 1999, 18, 1563.
321. Parallel-Stranded DNA Formed by New Base Pairs Related to the Isoguanosine-Cytosine or Isocytosine-Guanine Motifs
F. Seela, C. Wei, A. Melenewski, Y. He, R. Kröschel, E. Feiling, Nucleosides Nucleotides, 1999, 18, 1543.
320. 7-Deaza-2'-deoxyinosine: A Stable Nucleoside with the Ambiguous Base Pairing Properties of 2'-Deoxyinosine
F. Seela, C. Mittelbach, Nucleosides Nucleotides, 1999, 18, 425.
319. 5-Aza-7-deaza-2'-deoxyguanosine: Oligonucleotide Duplexes with Novel Base Pairs, Parallel Chain Orientation and Protonation Sites in the Core of a Double Helix
F. Seela, A. Melenewski, Eur. J. Org. Chem., 1999, 485.
318. Synthesis of oligonucleotides containing pyrazolo[3,4-d]pyrimidines: The influence of 7-substituted 8-aza-7-deazaadenines on the duplex structure and stability
F. Seela, M. Zulauf, J. Chem. Soc., Perkin Trans. 1, 1999, 479.
317. The High-Anti Conformation of 7-Halogenated 8-Aza-7-deaza-2'-deoxyguanosines: A Study of the Influence of Modified Bases on the Sugar Structure of Nucleosides
F. Seela, G. Becher, H. Rosemeyer, H. Reuter, G. Kastner, I. A. Mikhailopulo, Helv. Chim. Acta, 1999, 82, 105.
316. Different Conformations of 1-Deazaadenosine and its 2'-Deoxyribonucleoside in the Solid State and in Solution
F. Seela , H. Debelak, H. Reuter, G. Kastner, I. A. Mikhailopulo, Tetrahedron, 1999, 55, 1295.
315. 7-Halogenated 7-Deaza -2'-deoxyinosines
N. Ramzaeva, C. Mittelbach, F. Seela, Helv. Chim. Acta, 1999, 82, 12.
314. Dimeric Oligonucleotides Synthons Containing 2-Deoxy-3-O-Phosphonomethyl α-D-erythro-pentofuranosyl Nucleosides
I.A. Mikhailopulo, T.I. Kulak, O. V. Tkachenko, S. L. Sentyureva, F. Seela, Nucleosides Nucleotides, 1999, 18, 1253.
313. 7-Deazapurine 2'-deoxyribofuranosides are noncleavable competitive inhibitors of Escherichia coli purine nucleoside phosphorylase (PNP)
A. Bzowska, Z. Kazimierczuk, F. Seela, Acta Biochim. Polonica, 1998, 45, 755.
312. Synthesis of 7-alkynylated 8-aza-7-deaza-2'-deoxyadenosines via the Pd-catalysed cross-coupling reaction
F. Seela, M. Zulauf, J. Chem. Soc., Perkin Trans. 1, 1998, 3233.
311. N 7-DNA: Base-Pairing Properties of N 7-(2'-Deoxy-ß-D-erythro-pentofuranosyl)-Substituted Adenine Hypoxanthine, and Guanine in Duplexes with Parallel Chain Orientation
F. Seela, P. Leonard, Helv. Chim. Acta, 1998, 81, 2244.
310. Stabilisation of Duplex DNA by 7-Halogenated 8-Aza-7-deazaguanines
F. Seela, G. Becher, Chem. Commun., 1998, 2017.
309. Dissection of the Roles of Adenine Ring Nitrogen (N-1) and Exocyclic Amino (N-6) Moieties in the Interaction of 2-5A with RNase L
M.R. Player, E.N. Kalinichenko, T. L. Podkopaeva, I.A. Mikhailopulo, F. Seela, P.F. Torrence, Biochem. Biophys. Res. Commun., 1998, 245, 430.
308. 8-Azaadenosine and its 2'-Deoxyribonucleoside: Synthesis and Oligonucleotide Base-Pair Stability
F. Seela, I. Münster, U. Löchner, H. Rosemeyer, Helv. Chim. Acta, 1998, 81, 1139.
307. Facile Synthesis of 2'-Deoxynucleoside Analogs of pre Q
N. Ramzaeva, G. Becher, F. Seela, Synthesis, 1998, 1327.
306. 7-Deazaadenine-DNA: Bulky 7-Iodo Substituents or Hydrophobic 7-Hexynyl Chains are well Accommodated in the Major Groove of Oligonucleotide Duplexes
F. Seela, M. Zulauf, Chem. Eur. J., 1998, 4, 1781.
305. Parallel-Stranded Duplex DNA and Self-Assembled Quartet Structures Formed by Isoguanine and Related Bases
F. Seela, C. Wei, A. Melenewski, E. Feiling, Nucleosides Nucleotides, 1998, 17, 2045.
304. 7-Deazapurine Oligodeoxyribonucleotides: The Effects of 7-Deaza-8-methylguanine on DNA Structure and Stability
F. Seela, Y. Chen, C. Mittelbach, Helv. Chim. Acta, 1998, 81, 570.
303. 1-Deazaadenosine: Synthesis and Activity of Base-Modified Hammerhead Ribozymes
F. Seela, H. Debelak, N. Usman, A. Burgin, L. Beigelman, Nucleic Acids Res., 1998, 26, 1010.
302. Synthesis of 7-Halogenated 8-Aza-7-deaza-2'-deoxyguanosines and Related Pyrazolo[3,4-d]pyrimidine 2'-Deoxyribonucleosides
F. Seela, G. Becher, Synthesis, 1998, 207.
301. Parallel-stranded duplexes and quartet assemblies formed by oligonucleotides containing isoguanine
F. Seela, C. Wei, A. Melenewski, P. Leonard, Nucleic Acids Symp. Ser., 1997, 37, 149.
300. 7-Deazaisoguanine quartets: self-assembled oligonucleotides lacking the Hoogsteen motif
F. Seela, C. Wei, Chem. Commun., 1997, 1869.
299. ‘PURINES’
F. Seela, N. Ramzaeva, H. Rosemeyer, Houben-Weyl, Vol. E9b, 1998, pp. 304-550.
298. 7-Nitro-7-deaza-2'-deoxyadenosine and 8-Methyl-7-deaza-2'-deoxyguanosine: pyrrolo[2,3-d]pyrimidine Nucleosides with Different Sugar Conformations
F. Seela, H. Rosemeyer, M. Zulauf, Y. Chen, G. Kastner, H. Reuter, Liebigs Ann./Recueil, 1997, 2525.
297. Parallel-Stranded DNA Formed by a new Base Pair between Guanine and 5-Aza-7-deazaguanine
F. Seela, A. Melenewski, C. Wei, Bioorg. Med. Chem. Lett., 1997, 7, 2173.
296. 7-Deazaguanine DNA: Oligonucleotides with Hydrophobic or Cationic Side Chains
N. Ramzaeva, C. Mittelbach, F. Seela, Helv. Chim. Acta, 1997, 80, 1809.
295. Synthesis of 2',3'-Didehydro-2',3'-Dideoxyisoinosine and Oxidation of Fluorescent 2-Hydroxypurine Nucleosides by Xanthine Oxidase
F. Seela, Y. Chen, M. Sauer, Nucleosides Nucleotides, 1998, 17, 39.
294. 1-Deaza-3'-O-Methyladenosine: A Nucleoside with the Syn-Conformation in the Solid State and in Solution
F. Seela, H. Debelak, H. Reuter, G. Kastner, I.A. Mikhailopulo, Nucleosides Nucleotides, 1998, 17, 729.
293. Stereoelectronic Effects of Modified Purine Bases on the Sugar Conformation of Nucleosides: Pyrrolo[2,3-d]pyrimidines
H. Rosemeyer, F. Seela, J. Chem. Soc., Perkin Trans. 2, 1997, 2341.
292. Regioselectivity of the Mannich Reaction on Pyrrolo[2,3-d]pyrimidine Nucleosides Related to 7-Deaza-2'-deoxyadenosine or 7-Deaza-2'-deoxyguanosine
F. Seela, Y. Chen, M. Zulauf, Synthesis, 1997, 1067.
291. A 2'→5'-Adenylate Trimer with a Positively Charged 2'(3')-Terminal 8-(4-Aminobutyl)Aminoadenosine Residue: Synthesis,onformation and RNase L Binding
I.A. Mikhailopulo, E.N. Kalinichenko, T. L. Podkopaeva, M. Kelve, M. Saarma, M. Y. Lidaks, H. Rosemeyer, F. Seela, Nucleosides Nucleotides, 1997, 16, 1855.
290. Studies on the Base-Pairing Properties of N7-(2-Deoxy-β-D-erythro-pentofurano-syl)guanine (N7Gd)
F. Seela, P. Leonard, Helv. Chim. Acta, 1997, 80, 1301.
289. Four-Stranded DNA Formed by Isoguanine Quartets: Complex Stoichiometry, Thermal Stability and Resistance against Exonucleases
F. Seela, C. Wei, A. Melenewski, Origins of Life and Evolution of the Biosphere, 1997, 27, 597.
288. Methylated DNA: The Influence of 7-Deaza-7-methylguanine on the Structure and Stability of Oligonucleotides
F. Seela, Y. Chen, Helv. Chim. Acta, 1997, 80, 1073.
287. 1',5'-Anhydrohexitol Oligonucleotides: Hybridisation and Strand Displacement with Oligoribonucleotides, Interaction with RNase H and HIV Reverse Transcriptase
C. Hendrix, H. Rosemeyer, B.De Bouvere, A. Van Aerschot, F. Seela, P. Herdewijn, Chem. Eur. J., 1997, 3, 1513.
286. Stereoelectronic Effects of Modified Purines on the Sugar Conformation of Nucleosides and Fluorescence Properties
H. Rosemeyer, M. Zulauf, N. Ramzaeva, G. Becher, E. Feiling, K. Mühlegger, I. Münster, A.Lohmann, F. Seela, Nucleosides Nucleotides, 1997, 16, 821.
285. Steric and Stereoelectronic Effects of 7-Deazapurine Bases on the Sugar Conformation of 2'-Deoxynucleosides
H. Rosemeyer, N. Ramzaeva, M. Zulauf, H. Thomas, Y. Chen, C. Mittelbach, F. Seela, Nucleosides Nucleotides, 1997, 16, 1447.
284. Duplex Stability of Oligonucleotides Containing 7-substituted 7-deaza- and 8-Aza-7-deazapurine Nucleosides
F. Seela, N. Ramzaeva, M. Zulauf, Nucleosides Nucleotides, 1997, 16, 963.
283. Oligonucleotides Containing Consecutive 2'-Deoxyisoguanosine Residues: Synthesis, Parallel Duplex Formation and Identification of A d(T4iG4T4) Tetraplex
F. Seela, C. Wei, A. Melenewski, Nucleosides Nucleotides, 1997, 16, 1523.
282. Oligonucleotides Containing Consecutive 2’-Deoxyisoguanosine Residues: Synthesis, Duplexes with Parallel Chain Orientation and Aggregation
F. Seela, C. Wei, Helv. Chim. Acta, 1997, 80, 73.
281. Unexpected Dehalogenation of 3-Bromopyrazolo[3,4-d]pyrimidine Nucleosides during Nucleobase-anion Glycosylation
F. Seela, M. Zulauf, G. Becher, Nucleosides Nucleotides, 1997, 16, 305.
280. Oligonucleotides with Purine Nitrogen-7 as Glycosylation Site
F. Seela, P. Leonard, Nucleosides Nucleotides, 1997, 16, 669.
279. 1’,5’-Anhydrohexitol Oligonucleotides: Synthesis, Base Pairing and Recognition by Regular Oligodeoxyribonucleotides and Oligoribonucleotides
C. Hendrix, H. Rosemeyer, I. Verheggen, F. Seela, A. Van Aerschot, P. Herdewijn, Chem. Eur. J., 1997, 3, 110.
278. Isoguanine Quartets Formed by d(T4isoG4T4): Tetraplex Identification and Stability
F. Seela, A. Melenewski, C. Wei, Nucleic Acids Res., 1996, 24, 4940.
277. Synthesis and application of novel nucleoside phosphonates and phosphoramidites modified at the base moiety
F. Seela, Y. Chen, A. Melenewski, H. Rosemeyer, C. Wei, Acta Biochimica Polonica, 1996, 43, 45.
276. Xylose-DNA Containing the Four Natural Bases
F. Seela, M. Heckel, H. Rosemeyer, Helv. Chim. Acta, 1996, 79, 1451.
275. Oligonucleotides Containing 2'-Deoxyguanosine or 7-Deaza-2'-Deoxyisoguanosine: Base Pairing and Aggregation
F. Seela, C. Wei, Collect. Czech. Chem. Commun., 1996, 61, 114.
274. 7-Deazapurine DNA: Oligonucleotides Containing 7-Substituted 7-Deaza-2'-deoxyguanosine and 8-Aza-7-deaza-2'-deoxyguanosine
F. Seela, N. Ramzaeva, G. Becher, Collect. Czech. Chem. Commun., 1996, 61, 258.
273. Oligonucleotides Containing 7-Deazaguanine:The Role of 7-and 8-Methyl Groups during the B-Z Transition of DNA
F. Seela, Y. Chen, Collect. Czech. Chem. Commun., 1996, 61, 112.
272. Duplex-Stability of 7-Deazapurine DNA: Oligonucleotides Containing 7-Bromo or 7-Iodo-7-deazaguanine
F. Seela, N. Ramzaeva, Helv. Chim. Acta, 1996, 79, 1549.
271. Oligonucleotides containing 7- or 8-methyl-7-deazaguanine: steric requirements of major groove substituents on the DNA structure
F. Seela, Y. Chen, Chem. Commun., 1996, 2263.
270. Xylose-DNA: Comparison of the Thermody-namic Stability of Oligo(2'-deoxyxylo-nucleotide) and Oligo(2'-deoxyribo-nucleotide) Duplexes
A. Schöppe, H. J. Hinz, H. Rosemeyer, F. Seela, Eur. J. Biochem., 1996, 239, 33.
269. The DNA-Stabilising Nucleoside 7-Iodo-2’-deoxytubercidin: Its Structure in the Solid State and in Solution
F. Seela, M. Zulauf, H. Rosemeyer, H. Reuter, J. Chem. Soc., Perkin Trans. 2, 1996, 2373.
268. N7-DNA: Synthesis and Base Pairing of Oli-gonucleotides Containing N7-(2-Deoxy-β-D-erythro-pentofuranosyl)guanine (N7Gd)
F. Seela, P. Leonard, Helv. Chim. Acta, 1996, 79, 477.
267. Conformational Analysis of 3'-Deoxyribo-nucleosides Using 1D-NOE Difference Spec-troscopy
A. Kumar, S.B. Katti, H. Rosemeyer, F. Seela, Nucleosides Nucleotides, 1996, 15, 1595.
266. Palladium-Catalyzed Cross Coupling of 7-Iodo-2'-deoxytubercidin with Terminal Alkynes
F. Seela, M. Zulauf, Synthesis, 1996, 726.
265. Synthesis of 4-Substituted 1H-Benzimidazole 2'-Deoxyribonucleosides and Utility of the 4-Nitro Compound as Universal Base
F. Seela, W. Bourgeois, H. Rosemeyer, T. Wenzel, Helv. Chim. Acta, 1996, 79, 488.
264. Synthesis of 6-Substituted 1-Deazapurine 2'-Deoxyribonucleosides
T. Wenzel, F. Seela, Helv. Chim. Acta, 1996, 79, 169.
263. Synthesis of 1-Deazaadenosine Analogues of (2',5') ApApA
I. A. Mikhailopulo, E. N. Kalinichenko, T. L. Podkopaeva, H. Rosemeyer, T. Wenzel, F. Seela, Nucleosides Nucleotides, 1996, 15, 445.
262. Oligonucleotide Duplex Stability Controlled by the 7-Substituents of 7-Deazaguanine Bases
F. Seela, N. Ramzaeva, Y. Chen, Bioorg. & Med. Chem. Letters, 1995, 5, 3049.
261. Substituent Reactivity and Tautomerism of Isoguanosine and Related Nucleosides
F. Seela, C. Wei, Z. Kazimierczuk, Helv. Chim. Acta, 1995, 78, 1843.
260. 7-Substituted 7-Deaza-2'-deoxyguanosines: Regioselective Halogenation of Pyrrolo[2,3-d]pyrimidine Nucleosides
N. Ramzaeva, F. Seela, Helv. Chim. Acta, 1995, 78, 1083.
259. Oligonucleotides containing fluorescent 2'-deoxyisoinosine: solid-phase synthesis and duplex stability
F. Seela, Y. Chen, Nucleic Acids Res., 1995, 23, 2499.
258. Oligodeoxyribonucleotides Containing 4-Aminobenzimidazole in Place of Adenine: Solid-Phase Synthesis and Base Pairing
F. Seela, T. Wenzel, Helv. Chim. Acta, 1995, 78, 833.
257. 2-Chloro-2'-Deoxyadenosine: Synthesis and Antileukemic Activity of 8-Substituted Deriva-tives
Z. Kazimierczuk, J.A. Vilpo, F. Seela, Nucleosides Nucleotides, 1995, 14, 1403.
256. Duplex Stabilization of DNA: Oligo-nucleotides Containing 7-Substituted 7-Deazaadenines
F. Seela, H. Thomas, Helv. Chim. Acta, 1995, 78, 94.
255. Hoogsteen-Duplex DNA: Synthesis and Base Pairing of Oligo-deoxynucleotides Con-taining 1-Deaza-2'-deoxyadenosine
F. Seela, T. Wenzel, H. Debelak, Nucleosides Nucleotides, 1995, 14, 957.
254. 2'-Deoxyisoinosine: Synthesis of a Highly Fluorescent Nucleoside and its Incorporation into Oligonucleotides
F. Seela, Y. Chen, Nucleosides Nucleotides, 1995, 14, 863.
253. Xylose-DNA: Sequence-Dependent Duplex Stability as Function of Backbone Configura-tion
H. Rosemeyer, F. Seela, Nucleosides Nucleotides, 1995, 14, 1041.
252. Synthesis of 6-Substituted Purine N7-(2-Deoxy-β-D-ribonucleosides) via Anion Glycosylation and Anomerization during the N7/N9-Glycosyl Transfer
F. Seela, H. Winter, Nucleosides Nucleotides, 1995, 14, 129.
251. Synthesis and Photochemical Conversion of Oligonucleotides Containing 2-Chloro-2'-deoxyadenosine
N. Ramzaeva, H. Rosemeyer, F. Seela, Nucleosides Nucleotides, 1995, 14, 947.
250. Hoogsteen-Duplex DNA: Synthesis and Base Pairing of Oligonucleotides Containing 1-Deaza-2'-deoxyadenosine
F. Seela, T. Wenzel, Helv. Chim. Acta, 1994, 77, 1485.
249. Oligonucleotides with unnatural bases or an altered sugar-phosphate backbone
F. Seela, H. Debelak, H. Rosemeyer, H. Thomas, T. Wenzel, M. Zulauf, Nucleic Acids Symposium Series, 1994, 31, 151.
248. Photochemical Conversion of Oligonucleotides Containing 2-Chloro-2'-deoxyadenosine: Enhanced UV Sensitivity of a Modified Purine Base Induced by the Nearest Neighbor
N. Ramzaeva, F. Seela, Chem. Res. Toxicol., 1994, 7, 643.
247. Synthesis, Base Pairing, and Structural Transitions of Oligodeoxyribonucleotides Contain-ing 8-Aza-2'-deoxyguanosine
F. Seela, S. Lampe, Helv. Chim. Acta, 1994, 77, 1003.
246. Synthesis of Certain 5-Substituted 2'-Deoxytubercidin Derivatives
F. Seela, H. Thomas, Helv. Chim. Acta, 1994, 77, 897.
245. 1-(2'-Deoxy-β-D-xylofuranosyl)cytosine: Base Pairing of Oligonucleotides with a Configura-tionally Altered Sugar-Phosphate Backbone
F. Seela, K. Wörner, H. Rosemeyer, Helv. Chim. Acta, 1994, 77, 883.
244. Facile Synthesis of 2'-Deoxyisoguanosine and Related 2',3'-Dideoxyribonucleosides
F. Seela, B. Gabler, Helv. Chim. Acta, 1994, 77, 622.
243. Synthesis of 2'-Deoxyisoinosine and Related 2'-Deoxyribonucleosides
F. Seela, Y. Chen, U. Bindig, Z. Kazimierczuk, Helv. Chim. Acta, 1994, 77, 194.
242. Synthesis of Oligoribonucleotides Containing Isoguanosine
F. Seela, T. Fröhlich, Helv. Chim. Acta, 1994, 77, 399.
241. N7-DNA: Synthesis and Base Pairing of Oli-gonucleotides Containing 7-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine (N7Ad)
F. Seela, H. Winter, Helv. Chim. Acta, 1994, 77, 597.
240. Polycytidylate and Poly(7-deazaguanylate): A Pair of Complementary Templates
H. Rembold, R.K. Robins, F. Seela, L.E. Orgel, J. Mol. Evol., 1994, 38, 211.
239. 3-Deaza- and 7-Deazapurines: Duplex Stability of Oligonucleotides Containing Modified Adenine or Guanine Bases
T. Grein, S. Lampe, K. Mersmann, H. Rosemeyer, H. Thomas, F. Seela, Bioorg. Med. Chem. Lett., 1994, 4, 971.
238. 8-Aza-2'-deoxyguanosine and Related 1,2,3-Triazolo[4,5-d]pyrimidine 2'-Deoxyribofuranosides
F. Seela, S. Lampe, Helv. Chim. Acta, 1993, 76, 2388.
237. Synthesis and Application of Oligoribonucleo tides Containing Guanosine Analogues
J. A. Grasby, C.E. Pritchard, K. Mersmann, F. Seela, M.J. Gait, Collect. Czech. Chem. Commun., 1993, 58, 154.
236. 8-Azaguanine 2',3'-Dideoxyribonucleosides: Glycosylation of the 5-Amino-7-methoxy-3H-1,2,3-triazolo[4,5-d]pyrimidinyl Anion with 2,3-Dideoxy-D-glycero-pentofuranosyl Chloride
F. Seela, K. Mersmann, Helv. Chim. Acta, 1993, 76, 2184.
235. Synthesis of Oligoribonucleotides Containing soguanosine
F. Seela, T. Fröhlich, Collect. Czech. Chem. Commun., 1993, 58, 183.
234. 2'-Deoxyisoguanosine: Synthesis and Incorporation into Oligodeoxyribonucleotides
F. Seela, B. Gabler, Z. Kazimierczuk, Collect. Czech. Chem. Commun., 1993, 58, 170.
233. Oligonucleotides Containing 2'-Deoxyxylo-cytidine
F. Seela, K. Wörner, H. Rosemeyer, Collect. Czech. Chem. Commun., 1993, 58, 150.
232. 7-Deazaadenosine: Oligoribonucleotide Building Block Synthesis and Autocatalytic Hydrolysis of Base-Modified Hammerhead Ribozymes
F. Seela, K. Mersmann, J. Grasby, M.J. Gait, Helv. Chim. Acta, 1993, 76, 1809.
231. Pyrazolo[3,4-d]pyrimidine 2'-Deoxy- and 2',3'-Dideoxyribonucleosides: Studies on the Glycosylation of 4-Methoxypyrazolo[3,4-d]pyrimidine
F. Seela, H. Winter, M. Möller, Helv. Chim. Acta, 1993, 76, 1450.
230. 7-Deazaguanosine: Synthesis of an Oligoribonucleotide Building Block and Disaggregation of the UGGGGU G4 Structure by the Modified Base
F. Seela, K. Mersmann, Helv. Chim. Acta, 1993, 76, 1435.
229. Oligodeoxyribonucleotides Containing N7-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine
F. Seela, H. Winter, Bioorg. Med. Chem. Lett., 1993, 3, 273.
228. 1-Deaza-2'-deoxyadenosine: Phosphonate and Phosphoramidite Building Blocks for Solid-Phase Oligonucleotide Synthesis
F. Seela, T. Wenzel, Heterocycles, 1993, 36, 237.
227. Synthesis of 2'-Azido-2',3'-didehydro-2',3'-dideoxythymidine
I. A. Mikhailopulo, G. V. Zaitseva, E. V. Vaaks, J. Balzarini, E. De Clercq, H. Rosemeyer, F. Seela, Liebigs Ann. Chem., 1993, 513.
226. 1-Deaza and 3-Deazapurines in the Reaction of Microbiological Transglycosylation
I.A. Mikhailopulo, A.I. Zinchenko, S.B. Bokut, N.V. Dudchik, V.N. Baraj, E.N. Kalinichenko, H. Rosemeyer, F. Seela, Biotechn. Lett., 1992, 14, 885.
225. Synthesis of Phosphonates and Oligodeoxyribonucleotides Derived from 2'-Deoxyisoguanosine and 2'-Deoxy-2-haloadenosines
F. Seela, R. Mertens, Z. Kazimierczuk, Helv. Chim. Acta, 1992, 75, 2298.
224. Base-Modified Nucleosides Related to 2-Chloro-2'-deoxyadenosine
Z. Kazimierczuk, J. A. Vilpo, F. Seela, Helv. Chim. Acta, 1992, 75, 2289.
223. 8-Azaadenine 2',3'-Dideoxyribonucleosides: Synthesis via 1,2,3-Triazolo[4,5-d]pyrimidinyl Anions
F. Seela, K. Mersmann, Helv. Chim. Acta, 1992, 75, 1885.
222. Synthesis and Properties of Methylthiopyrazolo[3,4-d]pyrimidine 2'-Deoxy-β-D-ribonucleosides
F. Oertel, H. Winter, Z. Kazimierczuk, J. A. Vilpo, P. Richter, F. Seela, Liebigs Ann. Chem., 1992, 1165.
221. 2'-Deoxy-β-D-xylothymidinyl-(3',5')-2'-deoxy-β-D-xylothymidylate: Stereochemical Course of Dinucleoside Phosphonate Formation and Conformational Properties
H. Rosemeyer, I. Strodtholz, F. Seela, Bioorg. Med. Chem. Lett., 1992, 2, 1201.
220. 3-Deaza-2'-deoxyadenosine: Synthesis via 4-(Methylthio)-1H-imidazo[4,5-c]pyridine 2’-Deoxyribonucleosides and Properties of Oligonucleotides
F. Seela, T. Grein, S. Samnick, Helv. Chim. Acta, 1992, 75, 1639.
219. 1,7-Dideaza-2'-deoxyadenosine: Building Blocks for Solid-Phase Synthesis and Secon-dary Structure of Base-Modified Oligodeoxyribonucleotides
F. Seela, T. Wenzel, Helv. Chim. Acta, 1992, 75, 1111.
218. Structure of Lumazine N1(2'-Deoxy-D-ribonucleosides) (=1-(2’-Deoxy-D-ribofuranosyl)pteridine-2,4(1H,3H)-diones): A Revision of the Anomeric Configuration
X. Cao, W. Pfleiderer, H. Rosemeyer, F.Seela, W. Bannwarth, P. Schönholzer, Helv. Chim. Acta, 1992, 75, 1267.
217. Imidazo[1,2-a]pyrimidine 2'-Deoxyribo- and 2',3'-Dideoxyribonucleosides: Glycosylation of the Nucleobase Anion
F. Seela, R. Gumbiowski, Liebigs Ann. Chem., 1992, 679.
216. 9-(2-Deoxy-β-D-xylofuranosyl)adenine and 1-(2-Deoxy-β-D-xylofuranosyl)thymine: Phosphorylation and Stability
M. Krecmerova, F. Seela, Nucleosides Nucleotides, 1992, 11, 1393.
215. 7-Deaza-2'-deoxyadenosine and 3-deaza-2'-deoxyadenosine replacing dA within d(A6)-tracts: differential bending at 3'- and 5'-junctions of d(A6).d(T6) and B-DNA
F. Seela, T. Grein, Nucleic Acids Res., 1992, 20, 2297.
214. 7-Deazaguanosine: Phosphoramidite and Phosphonate Building Blocks for Solid-Phase Oligoribonucleotide Synthesis
F. Seela, K. Mersmann, Heterocycles, 1992, 34, 229.
213. Formation of an Unexpected 2-Deoxy-α-D-Threo-pentofuranosyl Azide by Reaction of O2,3’-anhydro-5'-O-trityl-2'-deoxycytidine with Lithium Azide
I. A. Mikhailopulo, G. V. Zaitseva, E. V. Vaaks, H. Rosemeyer, F. Seela, Nucleosides Nucleotides, 1992, 11, 273.
212. 9-(2'-Deoxy-β-D-xylofuranosyl)adenine Build-ing Blocks for Solid-Phase Synthesis and Properties of Oligo(2'-deoxyxylonucleotides)
H. Rosemeyer, M. Krecmerova, F. Seela, Helv. Chim. Acta, 1991, 74, 2054.
211. 7-Deazapurine containing DNA: efficiency of c7GdTP, c7AdTP, and c7IdTP incorporation during PCR-amplification and protection from endodeoxyribonuclease hydrolysis
F. Seela, A. Röling, Nucleic Acids Res., 1992, 20, 55.
210. Solid-Phase Synthesis of Oligo(2'-deoxyxylonucleotides) and PCR-Amplification of Base-Modified DNA-Fragments
F. Seela, H. Rosemeyer, M. Krecmerovà, A. Röling, Nucleic Acids Res. Symposium Series, 1991, 24, 87.
209. 3-Deazaguanine N7-and N9-(2'-Deoxy-β-D-ribofuranosides): Building Blocks for Solid- Phase Synthesis and Incorporation into Oligodeoxyribonucleotides
F. Seela, S. Lampe, Helv. Chim. Acta, 1991, 74, 1790.
208. 2'-Deoxyisoguanosine and Base-Modified Analogues: Chemical and Photochemical Synthesis
Z. Kazimierczuk, R. Mertens, W. Kawczynski, F. Seela, Helv. Chim. Acta, 1991, 74, 1742.
207. 3'-Substituted and 2',3'-Unsaturated 7- Deazaguanine 2',3'-Dideoxynucleosides: Syntheses and Inhibition of HIV-1 Reverse Transcriptase
F. Seela, H.-P. Muth, Helv. Chim. Acta, 1991, 74, 1081.
206. 1,7-Dideaza-2’,3’-dideoxyadenosine: Syntheses of Pyrrolo[2,3-b]pyridine 2',3'-Dideoxyfuranosides and Participation of Purine N(1) during HIV-1 Reverse Transcrip-tase Inhibition
F. Seela, R. Gumbiowski, Helv. Chim. Acta, 1991, 74, 1048.
205. 1-(2’-Deoxy-β-D-xylofuranosyl)thymine Build-ing Blocks for Solid-Phase Synthesis and Properties of Oligo(2'-Deoxyxylonucleotides)
H.Rosemeyer, F. Seela, Helv. Chim. Acta, 1991, 74, 748.
204. Kinetics and Mechanism of the Acid-catalysed Hydrolysis of Regioisomeric Benzotriazole and 8-Azaadenine Nucleosides
R. Käppi, Z. Kazimierczuk, P. Järvinen, F. Seela, H. Lönnberg, J. Chem. Soc., Perkin Trans. 2, 1991, 595.
203. Oligonucleotides with Modified Bases or Al-tered Sugar-Phosphate Backbone
F. Seela, H. Rosemeyer, T. Grein, A. Röling, R. Mertens, 1991.
202. Synthesis of 5-Amino-4-cyano-1-imidazolyl 2-Deoxy-β-D-ribofuranoside by Photolysis of 2-Aza-2'-deoxyadenosine or Glycosylation
Z. Kazimierczuk, F. Seela, Liebigs Ann. Chem., 1991, 695.
201. Syntheses of Pyrrolo[2,3-d]pyrimidine 2’,3’-Dideoxyribonucleosides Related to 2’,3’-Dideoxyadenosine and 2’,3’-Dideoxyguanosine and Inhibitory Activity of 5'-Triphosphates on HIV-1 Reverse Transcriptase
F. Seela, H.-P. Muth, A. Röling, Helv. Chim. Acta, 1991, 74, 554.
200. Diastereomerically Pure RP and SP Dinucleoside H-Phosphonates: The Stereochemical Course of their Conversion into P-Methylphosphonates, Phosphorothioates, and [18O] Chiral Phosphates
F. Seela, U. Kretschmer, J. Org. Chem., 1991, 56, 3861.
199. Stereoselective Synthesis of Indazole 2'-Deoxy-β-D-ribonucleosides: Glycosylation of the Nucleobase Anion
F. Seela, W. Bourgeois, Helv. Chim. Acta, 1991, 74, 315.
198. Synthesis of Allopurinol and 4-Amino-1H-pyrazolo[3,4-d]pyrimidine N1 and N2-(β-D-Arabinofuranosides)
F. Seela, H. Winter, Liebigs Ann. Chem., 1991, 105.
197. ‘7-Deaza-2'-deoxyguanosine; Synthesis of 7-Deazapurine Nucleosides under Phase-transfer Conditions’
F. Seela, H. Driller, H. Steker, in ‘Nucleic Acid Chemistry, Improved and New Synthetic Procedures, Methods, and Techniques’, Part 4, Eds. L. B. Townsend, R. S. Tipson, 1991, 302.
196. ‘4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-pyrazolo-[3,4-d]pyrimidine: Synthesis of the 3’-0'-Phosphoramidite Derivative of 2’Deoxy H-APP Ribonu-cleoside and its Incorporation into the Dodecamer d(c7z8A-T6)’
F. Seela, K. Kaiser, in ‘Nucleic Acid Chemistry, Improved and New Synthetic Procedures, Methods, and Techniques’, Part 4, Eds. L.B. Townsend, R. S. Tipson, 1991, p. 332.
195. Synthesis of Indole 2',3'-Dideoxyribonucleosides
F. Seela, W. Bourgeois, Synthesis, 1990, 10, 945.
194. Synthesis of ara-3,7-Dideazaadenosine and Related Pyrrolo[3,2-c]pyridine D-Arabinofuranosides
W. Bourgeois, F. Seela, J. Chem. Soc., Perkin Trans. 1, 1991, 279.
193. Kinetics and Mechanism for Acid-catalyzed Hydrolysis of Regioisomeric 2'-Deoxyribonucleosides of 8-Azaadenine and Substituted Benzotriazoles
R. Käppi, Z. Kazimierczuk, F. Seela, H. Lönnberg, Nucleosides Nucleotides, 1991, 10, 571.
192. 2,4-Disubstituted Pyrrolo[2,3-d]pyrimidine α-D-and β-D-Ribofuranosides Related to 7-Deazaguanosine
F. Seela, T. Soulimane, K. Mersmann, T. Jürgens, Helv. Chim. Acta, 1990, 73, 1879.
191. Stereochemistry of Oxidation of Diastereoisomeric d(TpA) Phosphonates with Sulphur and Iodine[18O] Water
F. Seela, U. Kretschmer, J. Chem. Soc., Chem. Comm., 1990, 17, 1154.
190. Synthesis of 3-Deaza-2'-deoxyadenosine and 3-Deaza-2',3'-dideoxyadenosine: Glycosylation of the 4-Chloroimidazo[4,5-c]pyridinyl Anion
F. Seela, H. Rosemeyer, S. Fischer, Helv. Chim. Acta, 1990, 73, 1602.
189. DNA-Fragments Resistant to Endodeoxyribonuclease Hydrolysis: PCR-Amplification using 7-Deaza-2'-deoxyguanosine triphosphate in Place of dGTP
F. Seela, A. Röling, Nucleosides Nucleotides, 1991, 10, 715.
188. Stereospecific Oxidation of Rp- and Sp-Dinucleoside H-Phosphonates to Phosphorothioates
F. Seela, U. Kretschmer, Nucleosides Nucleotides, 1991, 10, 711.
187. Synthesis of Pyrrolo[3,2-c]pyrimidine and Pyrazolo[3,4-d]pyrimidine β-D-Arabinonucleosides via Nucleobase Anion Glycosylation
F. Seela, W. Bourgeois, H. Winter, Nucleosides Nucleotides, 1991, 10, 713.
186. Base-Modified Purine 2',3'-Dideoxyribonucleosides: Synthesis via Deoxygenation or Direct Nucleobase Anion Glycosylation
F. Seela, H. Rosemeyer, R. Gumbiowski, K. Mersmann, H.-P. Muth, A. Röling, Nucleosides Nucleotides, 1991, 10, 409.
185. Synthesis of Indole, Indazole, and 3-Deazapurine 2'-Deoxy-β-D-ribo and 2',3'-Dideoxy-D-ribonucleosides
F. Seela, W. Bourgeois, H. Rosemeyer, T. Grein, Collect. Czech. Chem. Commun., 1990, 55, 37.
184. Determination of the Syn-Anti Equilibrium of Regular and Modified Nucleosides by 1D 1H-NOE-Spectroscopy
H. Rosemeyer, F. Seela, Collect. Czech. Chem. Commun., 1990, 55, 13.
183. Incorporation of a Complete Set of Deoxyadenosine and Thymidine Analogues Suitable for the Study of Protein Nucleic Acid Interactions into Oligodeoxynucleotides. Application to the EcoRV Restriction Endonuclease and Modification Methylase
P.C. Newman, V.U. Nwosu, D. M. Williams, R. Cosstick, F. Seela, B. A. Connolly, Biochemistry, 1990, 29, 9891.
182. Interaction of the EcoRV Restriction Endonuclease with the Deoxyadenosine and Thymidine Bases in Its Recognition Hexamer d(GATATC)
P.C. Newman, D.M. Williams, R.Cosstick, F. Seela, B. A. Connolly, Biochemistry, 1990, 29, 9902.
181. Configurational and Conformational Analysis of Regular and Modified Nucleosides by 1D-NOE Difference Spectroscopy
H. Rosemeyer, F. Seela, Nucleosides Nucleotides, 1990, 9, 417.
180. Base-Modified 2'-Deoxyribonucleosides in Bended DNA-Fragments: Differential Bending at 3'- and 5'-Junctions of H- and B-DNA
F. Seela, H. Rosemeyer, T. Grein, Nucleosides Nucleotides, 1990, 9, 411.
179. ‘Base-modified Purine 2'3'-Dideoxyribonucleoside 5'-Triphosphates: Selective Inhibitors of HIV Reverse Transcriptase’
F. Seela, W. Bourgeois, R. Gumbiowski, A. Mertens, H.-P. Muth, A. Röling, H. Rosemeyer, in ‘Progress in AIDS Research’, Ed. M. Schauzu, MMV Medizin Verlag, München 1990, p. 247.
178. Stereochemistry of Oxidation of Diastereoisomeric d(TpA) Phosphonates with Sulphur and Iodine-[18O]Water
F. Seela, U.Kretschmer, J. Chem. Soc., Chem. Commun., 1990, 17, 1154.
177. Orientation, recognition, and photoreaction of nucleolipids in model membranes
M. Ahlers, H. Ringsdorf, H. Rosemeyer, F. Seela, Colloid Polym. Sci., 1990, 268, 132.
176. Stereoselective Synthesis of 2-Azapurine 2'-Deoxy-β-D-ribonucleosides by Nucleobase-Anion Glycosylation
Z. Kazimierczuk, F. Seela, Liebigs Ann. Chem., 1990, 647.
175. Syn-Anti Conformational Analysis of Regular and Modified Nucleosides by 1D 1H NOE Difference Spectroscopy: A Simple Graphical Method Based on Conformationally Rigid Molecules
H. Rosemeyer, G. Toth, B. Golankiewicz, Z. Kazimierczuk, W. Bour-geois, U. Kretschmer, H.-P. Muth, F. Seela, J. Org. Chem., 1990, 55, 5784.
174. Facile Synthesis of Pyrrolo[2,3-d]pyrimidine and Pyrrolo[3,2-c]pyridine 2',3'-Dideoxyribonucleosides via Nucleobase Anion Glycosylation with 2,3-Dideoxy-D-glyceropentofuranosyl Chloride
F. Seela, W. Bourgeois, H.-P. Muth, H. Rosemeyer, Heterocycles, 1989, 29, 2193.
173. Synthesis of 8-Aza-1,3-dideaza-2'-deoxyadenosine and 5,6-Disubstituted Benzotriazole 2'-Deoxy-β-D-ribofuranosides via Nucleobase Anion Glycosylation
Z. Kazimierczuk, F. Seela, Helv. Chim. Acta, 1990, 73, 316.
172. Synthesis of 4-Substituted 2-Aminopyrrolo-[2,3-d]pyrimidine 2',3'-Dideoxyribonucleosides
F. Seela, H.-P. Muth, Liebigs Ann. Chem., 1990, 227.
171. Synthesis of 8-Aza-2'-deoxyadenosine and Related 7-Amino-3H-1,2,3-triazolo[4,5-d]pyrimidine 2'-Deoxyribofuranosides: Stereoselective Glycosylation via the Nucleo-base Anion
Z. Kazimierczuk, U. Bindig, F. Seela, Helv. Chim. Acta, 1989, 72, 1527.
170. Synthesis and Properties of Conformationally Locked 1,3-Bisalkyl-7-deazaxanthine 2'-Deoxy-D-ribofuranosides
F. Seela, U. Kretschmer, J. Heterocyclic Chem., 1990, 27, 479.
169. Echinomycin-induced hypersensitivity to osmium tetroxide of DNA fragments incapable of forming Hoogsteen base pairs
M.J.McLean, F. Seela, M. J. Waring, Proc. Natl. Acad. Sci. USA, 1989, 86, 9687.
168. Glycosylations of Ambident Anions of 2(1H)-and 4(1H)-Pyridone and Stereoselective Synthesis of 2(1H)-Pyrimidinone N-(2'-Deoxy-α-D-ribofuranoside)
F. Seela, U.Bindig, Liebigs Ann. Chem., 1989, 895.
167. Stereoselective Glycosylation of Nitrobenzimidazole Anions: Synthesis of 1,3-Dideaza-2'-deoxyadenosine and Related 2'-Deoxyribofuranosides
F. Seela, W. Bourgeois, Synthesis, 1989, 912.
166. 2',3'-Dideoxy-3'-fluorotubercidin and Related Dideoxyribonucleosides: Synthesis via a 2'-Deoxy-3'-oxoribofuranoside Intermediate and Conformation Studies
H. Rosemeyer, F. Seela, Helv. Chim. Acta, 1989, 72, 1084.
165. 2'-Deoxy-β-D-ribofuranosides of N6-Methylated 7-Deazaadenine and 8-Aza-7-deazaadenine: Solid-Phase Synthesis of Oligodeoxyribonucleotides and Properties of Self-Complementary Duplexes
F. Seela, K. Kaiser, U. Bindig, Helv. Chim. Acta, 1989, 72, 868.
164. Alternating d(G-C)3 and d(C-G)3 hexanucleotides containing 7-deaza-2'-deoxyguanosine or 8-aza-7-deaza 2'-deoxyguanosine in place of dG
F. Seela, H. Driller, Nucleic Acids Res., 1989, 17, 901.
163. Synthesis of 3,7-Dideaza-2'-deoxyadenosine and Related Pyrrolo[3,2-c]pyridine 2'-Deoxyribo- and 2',3'-Dideoxyribonucleosides
F. Seela, W. Bourgeois, Synthesis, 1988, 938.
162. Assignment of Anomeric Configuration of D-Ribo-, Arabino-, 2'-Deoxyribo-, and 2',3'-Dideoxyribonucleosides by NOE Difference Spectroscopy
H. Rosemeyer, G. Toth, F. Seela, Nucleosides Nucleotides, 1989, 8, 587.
161. Synthesis of 1,7-Dideaza-2’-deoxyadenosine and Related Pyrrolo[2,3-b]pyridine 2’-Deoxy-β-D-ribonucleosides: Stereoselective Phase-transfer Glycosylation via the Nucleobase Anion
F. Seela, R. Gumbiowski, Heterocycles, 1989, 29, 795.
160. Bending of Oligonucleotides Containing an Isosteric Nucleobase: 7-Deaza-2'-deoxyadenosine Replacing dA within d(A)6- Tracts
F. Seela, H. Berg, H. Rosemeyer, Biochemistry, 1989, 28, 6193.
159. Analysis of the recognition mechanism in-volved in the EcoRV catalyzed cleavage of DNA using modified oligodeoxynucleotides
A. Fliess, H. Wolfes, F. Seela, A. Pingoud, Nucleic Acids Res., 1988, 16, 11781.
158. Unambiguous Assignment of Anomeric Configuration of Nucleosides by NOE-Difference Spectroscopy
G. Toth, H. Rosemeyer, F. Seela, Nucleosides Nucleotides, 1989, 8, 1091.
157. Synthesis of Pyrrolo[3,2-c]pyridine 2'-Deoxy-D-ribo-, 2',3'-Dideoxy-D-ribo-, and D-Arabinofuranosyl Nucleosides
F. Seela, W. Bourgeois, T. Jürgens, Nucleosides Nucleotides, 1989, 8, 1089.
156. Synthesis of Pyrrolo[2,3-b]pyridine Nucleo-sides by Solid-Liquid Phase-Transfer lycosy-ation and Deoxygenation of 4-chloropyrrolo[2,3-d]pyrimidine 2'-Deoxyribofuranosides
F. Seela, R. Gumbiowski, H.-P. Muth, W.Bourgeois, Nucleosides Nucleotides, 1989, 8, 1087.
155. Pyrazolo[3,4-d]pyrimidine 2'-Deoxyribo- and 2',3'-Dideoxyribofuranosides: Synthesis and Application to Oligonucleotide Chemistry
F. Seela, H. Driller, K. Kaiser, H.Rosemeyer, H. Steker, Nucleosides Nucleotides, 1989, 8, 789.
154. 8-Aza-7-deazaadenine N8-and N9-(β-D-2'-Deoxyribofuranosides): Building Blocks for Automated DNA-Synthesis and Properties of Oligodeoxyribonucleotides
F. Seela, K. Kaiser, Helv. Chim. Acta, 1988, 71, 1813.
153. Stereoselective Synthesis of Pyrrolo[2,3-d]pyrimidine α-and β-D-Ribonucleosides from Anomerically Pure D-Ribofuranosyl Chlorides: Solid-Liquid Phase-Transfer Glycosylation and 15N-NMR Spectra
H. Rosemeyer, F. Seela, Helv. Chim. Acta, 1988, 71, 1573.
152. 8-Aza-7-deaza-2'-deoxyguanosine: Phosphoramidite Synthesis and Properties of Octanucleotides
F. Seela, H. Driller, Helv. Chim. Acta, 1988, 71, 1191.
151. 8-Aza-7-deaza-2',3'-dideoxyguanosine: Deoxygenation of its 2'-Deoxy-β-D-ribofuranoside
F. Seela, H. Driller, Helv. Chim. Acta, 1988, 71, 757.
150. 8-Aza-7-deaza-2',3'-dideoxyadenosine: Synthesis and Conversion into Allopurinol 2',3'-Dideoxyribofuranoside
F. Seela, K. Kaiser, Chem. Pharm. Bull., 1988, 36, 4153.
149. 7-Deaza-2'-deoxy-O6-methylguanosine: Selective N2-Formylation via a Formamidine, Phosphoramidite Synthesis and Properties of Oligonucleotides
F. Seela, H. Driller, Nucleosides Nucleotides, 1989, 8, 1.
148. Synthesis of 6-Substituted 7-Carbapurine 2',3'-Dideoxynucleosides: Solid-Liquid Phase-Transfer Glycosylation of 4-Chloropyrrolo[2,3-d]pyrimidine and Deoxygenation of its 2'-Deoxyribofuranoside
F. Seela, H.-P. Muth, U. Bindig, Synthesis, 1988, 670.
147. 7-Carbapurine Ribofuranosides: Synthesis by Solid-Liquid Phase-Transfer Glycosylation and 15N-NMR Spectra
F. Seela, H. Rosemeyer, A. Biesewig, T. Jürgens, Nucleosides Nucleotides, 1988, 7, 581.
146. Solid-phase methods for sequencing nucleic acids VIII. CCS paper-supported degradation of oligodeoxyribonucleotides containing 2'-deoxytubercidin
A. Rosenthal, H. Billwitz, A. Kehne, F. Seela, Nucleic Acids Res., 1988, 16, 1631.
145. Synthesis of 5-aza-7-deazapurine and 3,7-dideazapurine 2'-deoxyribofuranosides by solid-liquid phase-transfer glycosylation
F. Seela, H. Rosemeyer, W. Bourgeois, Nucleic Acids Res. Symp. Ser., 1987, 18, 49.
144. 15N-NMR spectra of wyosine and related ribonucleosides
B. Golankiewicz, W. Folkman, H. Rosemeyer, F. Seela, Nucleic Acids Res., 1987, 15, 9075.
143. 2'-Deoxy-3,7-dideazaadenosine - synthesis and NMR assignment
F. Seela, W. Bourgeois, Nucleic Acids Res., 1987, 15, 7208.
142. Synthese von 7-Desaza-2',3'-didesoxyguanosin durch Desoxygenierung seines 2'-Desoxy-β-D-ribofuranosids
F. Seela, H.-P. Muth, Liebigs Ann. Chem., 1988, 215.
141. Dodecanucleotides containing (E)-5-(2-Bromovinyl)-2'-deoxyuridine: Influence of a Bulky Major Groove Substituent on Duplex Stability and Endodeoxyribonuclease Eco RI Recognition
F. Seela, H. Driller, W. Herdering, E. De Clercq, Nucleosides Nucleotides, 1988, 7, 347.
140. N6-(Carbamoylmethyl)-2'-deoxyadenosine - a Rare DNA Constituent: Phosphoramidite Synthesis and Properties of Palindromic Dodecanucleotides
F. Seela, W. Herdering, A. Kehne, Helv. Chim. Acta, 1987, 70, 1649.
139. 2'-Deoxy-3,7-dideazanebularine and 2'-Deoxy-3,7-dideazainosine: Synthesis of Pyrrolo-[3,2-c]pyridine β-D-2'-Deoxyribofuranosides by Solid-liquid Phase-Transfer Glycosylation
F. Seela, W. Bourgeois, Heterocycles, 1987, 26, 1755.
138. Liquid-Liquid and Solid-Liquid Phase-transfer Glycosylation of Pyrrolo[2,3-d]pyrimidines: Stereospecific Synthesis of 2-Deoxy-β-D-ribofuranosides related to 2'-Deoxy-7-carba-guanosine
F. Seela, B. Westermann, U. Bindig, J. Chem. Soc., Perkin Trans 1, 1988, 697.
137. 5-Aza-7-deaza-2'-deoxyguanosine: Studies on the Glycosylation of Weakly Nucleophilic Imidazo[1,2-a]-s-triazinyl Anions
H. Rosemeyer, F. Seela, J. Org. Chem., 1987, 52, 5136.
136. Oligodeoxyribonucleotides containing 1,3-propanediol as nucleoside substitute
F. Seela, K. Kaiser, Nucleic Acids Res., 1987, 15, 3113.
135. 7-Deaza-2'-deoxyguanosine-5'-Triphosphate: Enhanced Resolution in M13 Dideoxy Sequencing
P. J. Barr, R.M. Thayer, P. Laybourn, R. C. Najarian, F. Seela, D. R. Tolan, BioTechniques, 1986, 4, 428.
134. Dextran-linked 7-deazaguanine - a polymer-bound inhibitor of xanthine oxidase
H. Rosemeyer, K. Kaiser, F. Seela, Int. J. Bio. Macromol., 1987, 9, 205.
133. Phosphoramidites of [18O] chiral (RP)- and (SP)-configurated Dimer-blocks and their Use in automated Oligonucleotide Synthesis
F. Seela, A. Kehne, W. Herdering, U. Kretschmer, Nucleosides Nucleotides, 1987, 6, 451.
132. Oligomers Containing 2'-Deoxyinosine-Isosteres as ambiguous Nucleoside or 1,3-Propanediol as Nucleoside Substitute
F. Seela, K. Kaiser, Nucleosides Nucleotides, 1987, 6, 447.
131. Synthesis and Application of Isosteric Purine 2'-Deoxyribofuranosides
F. Seela, U. Bindig, H. Driller, W. Herding, K. Kaiser, A. Kehne, H. Rosemeyer, H. Steker, Nucleosides Nucleotides, 1987, 6, 11.
130. 2-Amino-2'-desoxytubercidin und verwandte Pyrrolo[2,3-d]pyrimidinyl-2’-desoxyribofuranoside
F. Seela, H. Steker, H. Driller, U. Bindig, Liebigs Ann. Chem., 1987, 15.
129. Synthesis of 2'-Deoxyribofuranosides of 8-Aza-7-deazaguanine and Related Pyrazolo-[3,4-d]pyrimidines
F. Seela, H. Steker, Helv. Chim. Acta, 1986, 69, 1602.
128. Palindromic Octa- and Dodecanucleotides Containing 2'-Deoxytubercidin: Synthesis, Hairpin Formation, and Recognition by the Endodeoxyribonuclease Eco RI
F. Seela, A. Kehne, Biochemistry, 1987, 26, 2232.
127. Structures of 2'-Deoxytubercidin (I) and 2'-Deoxytubercidin Dihydrate (II)
V. Zabel, W.Saenger, F. Seela, Acta Cryst. (C), 1987, 43, 131.
126. ‘Regio- and Stereospecific Synthesis of 7-Deazapurine 2'-Deoxyribonucleosides and Incorporation of Nucleoside Isosteres into Oligonucleotides’
F. Seela, H. Driller, A. Kehne, S. Menkhoff, J. Ott, H.-D. Winkeler, in ‘Chemical Synthesis in Molecular Biology’, Eds. H. Blöcker, R. Frank, H.-J. Fritz, Verlag Chemie, 1987, p. 29.
125. ‘Spontaneous Hydroxylation after Intramolecu-lar Cyclisation of 9-[2-(Carboxyethyl)]-hypoxanthine and Isosteres thereof’
H. Rosemeyer, K. Kaiser, U. Kretschmer, F. Seela, in ‘Bioorganic Heterocycles’, 1986, p. 253.
124. 2'-Desoxyribofuranoside des 6-Oxoallopurinols und verwandter 4,6-substituierter Pyrazolo-[3,4-d]pyrimidine
F. Seela, S. Menkhoff, Liebigs Ann. Chem., 1986, 1213.
123. Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP
S. Mizusawa, S. Nishimura, F. Seela, Nucleic Acids Res., 1986, 14, 1319.
122. Palindromic oligonucleotides containing 7-deaza-2'-deoxyguanosine: solid-phase synthesis of d[(p)GG*AATTCC)] octamers and recognition by the endodeoxyribonuclease EcoRI
F. Seela, H. Driller, Nucleic Acids Res., 1986, 14, 2319.
121. Self-complementary Oligomers Containing 7-Deaza-2'-deoxyguanosine or 2'-Deoxytubercidin
F. Seela, H. Driller, A. Kehne, K. Kaiser, Chemica Scripta, 1986, 26, 173.
120. Phosphoramidites of base modified 2'-deoxyinosine isosteres and solid-phase synthesis of d(GCI*CGC) oligomers containing an ambiguous base
F. Seela, K. Kaiser, Nucleic Acids Res., 1986, 14, 1825.
119. Furanoside-Pyranoside Isomerization of Tubercidin and its 2'-Deoxyderivatives: Influ-ence of Nucleobase and Sugar Structure on the Proton-catalysed Reaction
F. Seela, S. Menkhoff, S. Behrendt, J. Chem. Soc., Perkin Trans. 2, 1986, 525.
118. ‘4-Amino-7-β-D-arabinofuranosylpyrrolo- [2,3-d]pyrimidine - Synthesis of Ara-Tubercidin by Phase-Transfer Glycosylation’
F. Seela, H.-D. Winkeler, in ‘Nucleic Acid Chemistry, Improved and New Synthetic Pro-cedures, Methods, and Techniques’, Part 3, Eds. L. B. Townsend, R. S. Tipson, Wiley-Interscience, 1986, p. 209.
117. Cyclisation of 7-Deazaxanthine-9-propionic Acid to an Active-Site-Directed, Irreversibly Acting Inhibitor of Xanthine Oxidase
H. Rosemeyer, U. Kretschmer, F. Seela, Helv. Chim. Acta, 1985, 68, 2165.
116. Phosphoramidites of Chiral(RP)- and (SP)-Configurated d(T[P-18O]-A): Synthesis, Configurational Assignment, and Use as Dimer Blocks in Oligonucleotide Synthesis
W. Herdering, A. Kehne, F. Seela, Helv. Chim. Acta, 1985, 68, 2119.
115. [18O]Chiral Phosphate in d(CpA) and d(TpA): Synthesis via Phosphite Triesters and Assignment of Configuration
W. Herdering, F. Seela, J. Org. Chem., 1985, 50, 5314.
114. Hydrolytic Cleavage of 6-Oxopurines after Intramolecular Acylation at N-3
H. Rosemeyer, F. Seela, Heterocycles, 1985, 23, 2669.
113. Synthesis and Hydrolytic Stability of 4-Substituted Pyrazolo[3,4-d]pyrimidine 2'-Deoxyribofuranosides
F. Seela, H. Steker, J. Chem. Soc., Perkin Trans. 1, 1985, 2573.
112. A Nucleolipid with Antiviral Acycloguanosine as Head Group - Synthesis and Liposome Formation
H. Rosemeyer, M. Ahlers, B. Schmidt, F. Seela, Angew. Chem. Int. Ed., 1985, 24, 501.
111. Ein Nucleolipid mit dem antiviralen Acycloguanosin als Kopfgruppe - Synthese und Liposomenbildung
H. Rosemeyer, M. Ahlers, B. Schmidt, F. Seela, Angew. Chem., 1985, 97, 500.
110. Facile Synthesis of 2'-Deoxyribofuranosides of Allopurinol and 4-Amino-1H-pyrazolo[3,4-d]pyrimidine via Phase-Transfer Glycosy-lation
F. Seela, H. Steker, Helv. Chim. Acta, 1985, 68, 563.
109. Cyclic Nucleotide Specificity of the Activator and Catalytic Sites of a cGMP-stimulated cGMP-Phosphodiesterase from Dictyostelium discoideum
F. Kesbeke, J. Baraniak, R. Bulgakov, B. Jastorff, M. Morr, G.P. Petridis, W. J. Stec, F. Seela, J. M. Van Haastert, Eur. J. Biochem., 1985, 151, 179.
108. Spontane Öffnung des Pyrimidinringes in Pyrrolo[2,3-d]pyrimidinen nach intramolekularer Acylierung
H. Rosemeyer, K. Kaiser, F. Seela, V. Zabel, W. Saenger, Helv. Chim. Acta, 1985, 68, 534.
107. Oligomers with Alternating Thymidine and 2'-Deoxytubercidin: Duplex Stabilization by a 7-Deazapurine Base
F. Seela, A. Kehne, Biochemistry, 1985, 24, 7556.
106. Ein Purin/7-Desazapurin-Dinucleosid-Monophosphat mit 2-Amino-7H-pyrrolo-[2,3-d]pyrimidin als fluoreszierender Base
F. Seela, U. Engelke, Liebigs Ann. Chem., 1985, 1175.
105. Solid-phase synthesis of the self-complementary hexamer d(c7GpCpc7GpCpc 7GpC) via the 0-3'-phosphoramidite of 7-deaza-2'-deoxyguanosine
F. Seela, H. Driller, Nucleic Acids Res., 1985, 13, 911.
104. Spontaneous Hydroxylation of a Cyclization Intermediate of Allopurinol
H. Rosemeyer, K. Kaiser, F. Seela, J. Org. Chem., 1985, 50, 1847.
103. 7-Desaza-Isostere von 2'-Desoxyxanthosin und 2'-Desoxyspongosin-Synthese via Glycosylierung von 2,4-Dichlor-7H-pyrrolo[2,3-d]pyrimidin
F. Seela, H. Driller, U. Liman, Liebigs Ann. Chem., 1985, 312.
102. Synthesis of the β-D-Deoxyribofuranosides of 6-Amino-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one - A New Isostere of 2'-Deoxyguanosine
F. Seela, H. Steker, Heterocycles, 1985, 23, 2521.
101. Synthese von 7-Desaza-2'-desoxyinosin durch Phasentransferglycosylierung
F. Seela, S. Menkhoff, Liebigs Ann. Chem., 1985, 1360.
100. 2'-Desoxytubercidin : Synthese des O-3'-Phosphoramidites und Kondensation zu 2'-Desoxytubercidylyl(3'→5')-2'-Desoxytubercidin
F. Seela, A. Kehne, Tetrahedron, 1985, 41, 5387.
99. Assignment of 13C Chemical Shifts of α-D-Ribonucleoside Sugar Carbons by 1J(CH) Coupling Constants
F. Seela, W. Bussmann, Nucleosides Nucleotides, 1985, 4, 391.
98. Oxygen Chiral Phosphate in Ribo- and 2'-Deoxyribonucleoside Monophosphates by Oxidation of Phosphite Intermediates
F. Seela, J.Ott, B. V. L. Potter, W. Herdering, Nucleosides Nucleotides, 1985, 4, 131.
97. Synthesis of 2'-Deoxy-1-deazawyosine; A Stabile 2'-Deoxyisostere of a Rare tRNA Con-stituent
F. Seela, W. Bussmann, Tetrahedron, 1985, 41, 935.
96. Dextranverknüpftes N6-(2-Isopentenyl)adenosin - ein polymergebundener Antimetabolit mit „Sollbruchstelle“
H. Rosemeyer, F. Seela, Angew. Chem., 1984, 96, 365.
95. Anomere Tubercidine mit 2-Methylthio und N4-( ∆2-Isotopentenyl)rest
F. Seela, W. Bussmann, Liebigs Ann. Chem., 1984, 1972.
94. Synthesis of 2'-Deoxyribonucleosides of Allopurinol by Phase-Transfer Glycosylation
F. Seela, H. Steker, Tetrahedron Lett., 1984, 25, 5017.
93. Isomeric N-Methyl-7-deazaguanines: Synthesis, Structural Assignment, and Inhibitory Activity on Xanthine Oxidase
F. Seela, W. Bussmann, A. Götze, H. Rosemeyer, J. Med. Chem., 1984, 27, 981.
92. Synthese von 2'-Desoxyribofuranosiden des 7H-Pyrrolo[2,3-d]pyrimidins: Einfluß des C-2 Substituenten auf die Fluoreszenz
F. Seela, H. Steker, Liebigs Ann. Chem., 1984, 1719.
91. Synthesis of 7-deaza-2'-deoxyguanosine by phasetransfer glycosylation and preparation of suitable derivatives for oligonucleotide synthesis
F. Seela, H.-D. Winkeler, H. Driller, S. Menkhoff, Nucleic Acids Res. Symp. Ser., 1984, 14, 245.
90. Synthesis of 7-Deazatriacanthine and Restricted Rotation of Amino Groups in Pyrrolo[2,3-d]pyrimidines
F. Seela, W. Bussmann, Nucleosides Nucleotides, 1984, 3, 195.
89. 7-(β-D-Arabinofuranosyl)-2,4-dichlor-7H-pyrrolo[2,3-d]pyrimidin - Synthese, selektiver Halogenaustausch und Einfluß glyconischer Schutzgruppen auf die Reaktivität des Aglycons
F. Seela, H. Driller, Liebigs Ann. Chem., 1984, 722.
88. Synthese und Furanosid/Pyranosid-Isomerisierung von 7-Desaza-2’-desoxy-7-methylguanosin
H.-D. Winkeler, F. Seela, Liebigs Ann. Chem., 1984, 708.
87. Polymer-linked acycloguanosine
H. Rosemeyer, F. Seela, Makromol. Chem., 1984, 185, 687.
86. (2'→5') und (3'→5')-Tubercidylyl-tubercidine - Synthese über Phosphit-Triester und Untersuchungen zur Sekundärstruktur
F. Seela, J. Ott, E. Hißmann, Liebigs Ann. Chem., 1984, 692.
85. ara-7-Desazaxanthosin - ein Xanthin-nucleosid mit stabiler N-glycosylischer Bindung
F. Seela, U. Liman, Liebigs Ann. Chem., 1984, 273.
84. ara-7-Desazanebularin - Synthese eines fluoreszierenden Pyrrolo[2,3-d]pyrimidin-Nucleosids durch Phasentransferglyco-sylierung
F. Seela, H. Steker, Liebigs Ann. Chem., 1983, 1576.
83. 2’,3'-O-Silylierung von Tubercidin mit tert-Butyl(chlor)dimethylsilan
F. Seela, E. Hißmann, J. Ott, Liebigs Ann. Chem., 1983, 1169.
82. 2'-Desoxytubercidin - Synthese eines 2'-Desoxyadenosin-Isosteren durch Phasentransferglycosylierung
F. Seela, A. Kehne, Liebigs Ann. Chem., 1983, 876.
81. Poly(2-methylthio-7-deazainosinic acid) - hydrophobic stabilization of polynucleotide secondary structure by the 2-methylthio group
F. Seela, J. Ott, D. Franzen, Nucleic Acids Res. 1983, 11, 6107.
80. ‘Synthesis of Pyrrolo[2,3-d]pyrimidine Nucleosides by Phasetransfer Glycosylation and their Function in Polynucleotides’
F. Seela, H.-D. Winkeler, J. Ott, Q.-H. Tran-Thi, D. Hasselmann, D. Franzen, W. Bussmann, in ‘Nucleosides, Nucleotides and Their Biological Application’, Eds.J. L. Rideout, D. W. Henry, L. M. Beacham III, Academic Press 1983, p. 181.
79. ‘Dextran-Bound Purine Nucleosides as Sub-strates and Inhibitor of Adenosine Deaminase’
H. Rosemeyer, F. Seela, in ‘Affinity Chromatography and Biological Recognition’, Eds. I. M. Chaiken, M. Wilchek, I. Parikh, Academic Press, New York, 1983.
78. Oxygen Chiral Phosphate in Uridylyl-(3'→5')adenosine by Oxidation of a Phosphite Intermediate: Synthesis and Absolute Configu-ration
F. Seela, J. Ott, B. Potter, J. Am. Chem. Soc., 1983, 105, 5879.
77. Methylated 7-Deazahypoxanthines as Regiochemical Probes of Xanthine Oxidase
H. Rosemeyer, F. Seela, Eur. J. Biochem., 1983, 134, 513.
76. Synthese von Acyclo-7-desazaguanosin durch regiospezifische Phasentransferalkylierung von 2-Amino-4-methoxy-7H-pyrrolo-[2,3-d]-pyrimidin
F. Seela, A. Kehne, H.-D. Winkeler, Liebigs Ann. Chem., 1983, 137.
75. 2-Amino-7-β-D-arabinofuranosyl-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine: A facile Prepa-ration and Anomerisation of a 7-Deazapurine Nucleoside
F. Seela, H.-D. Winkeler, Carbohydr. Res., 1983, 118, 29.
74. Synthesis of 2-Amino-7-(2'-deoxy-β-D-erythro-pentofuranosyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, a New Isostere of 2'-Deoxyguanosine
H.-D. Winkeler, F. Seela, J. Org. Chem., 1983, 48, 3119.
73. N4-(3-Methyl-2-butenyl)-2-(methylthio)tubercidin and its α-Anomer - 7-Deazapurine Nucleosides with Potential Anticytokinin Activity
F. Seela, W. Bussmann, Nucleosides Nucleotides, 1982, 1, 253.
72. 4-Amino-7-(rac-2,3-dihydroxypropyl)-7H-pyrrolo[2,3-d]pyrimidin Synthese von Acylo-tubercidin
F. Seela, A. Kehne, Liebigs Ann. Chem., 1982, 1940.
71. Synthese des α-Anomeren von ara-7-Desazaguanosin durch Phasentransferglyco-sylierung - Steuerung des Anomerenverhältnisses durch das quartäre Ammoniumsalz
F. Seela, H.-D. Winkeler, Liebigs Ann. Chem., 1982, 1634.
70. 4,4'-Dimethoxy-2,2'-bis(methylthio)-7,7'-methylen-di(7H-pyrrolo[2,3-d]pyrimidin) – Phasentransferkatalysierte Aglyconverbrückung in Dichlormethan
F. Seela, S. Menkhoff, Liebigs Ann. Chem., 1982, 1405.
69. Dextran-Linked Purine-Nucleosides as Sub-strates and Inhibitors of Adenosine Deaminase
H. Rosemeyer, E.Körnig, F. Seela, Eur. J. Biochem., 1982, 127, 185.
68. 2-Methylthio-7-desazainosin und sein α-Anomer - Debenzylierung von Thionucleosiden mit Bortrichlorid
F. Seela, S. Menkhoff, Liebigs Ann. Chem., 1982, 813.
67. 7-Deazaguanosine-3',5'-phosphate - An Isoteric cGMP Analogue with High Affinity for Cyclonucleotide Phosphodiesterase
Q.-H. Tran-Thi, D. Franzen, F. Seela, Angew. Chem. Int. Ed., 1982, 21, 367.
66. 7-Desazaguanosin-3',5'-phosphat - ein isosteres cGMP-Analogon mit hoher Affinität zu Cyclonucleotide Phosphodiesterase
Q.-H. Tran-Thi, D. Franzen, F. Seela, Angew. Chem., 1982, 945.
65. Adenosine Deaminase Covalently Linked to Soluble Dextran - The Effect of Immobilization on Thermodynamic and Kinetic Parameters
H. Rosemeyer, E. Körnig, F. Seela, Eur. J. Biochem., 1982, 122, 375.
64. Poly(adenylic acids) containing the antibiotic tubercidin - base pairing and hydrolysis by nuclease S1
F. Seela, J. Ott, D. Franzen, Nucleic Acids Res., 1982, 10, 1389.
63. Poly(7-deazaguanylic acid), the Homopolynucleotide of the Parent Nucleoside of Queuosine
F. Seela, Q.-H. Tran-Thi, D. Franzen, Biochemistry, 1982, 21, 4338.
62. Regioselektive Synthese der N-Monomethyl-Derivate des 7-Desazahypoxanthins
F. Seela, W. Bussmann, A. Götze, Liebigs Ann. Chem., 1982, 805.
61. 2-Amino-7-(β-D-arabinofuranosyl)pyrrolo[2,3-d]pyrimidin-4(3H)-one. Synthesis of ara-7-Deazaguanosine via Phase-Transfer Glycosylation
F. Seela, H.-D. Winkeler, J. Org. Chem., 1982, 47, 226.
60. Synthesis of ara tubercidin and its α-anomer by phase transfer glycosylation of pyrrolo[2,3-d]pyrimidines
F. Seela, H.-D. Winkeler, Nucleic Acids Res. Symp. Ser., 1981, 9, 107.
59. Synthese von α-7-Desazaguanosin und Ein-fluß der Basenkonzentration auf die Phasentransferglycosylierung
F. Seela, D. Hasselmann, H.-D. Winkeler, Liebigs Ann. Chem., 1982, 499.
58. Bis(isopropylidene adenosine) - A Novel Base-Stacked Dinucleoside with Two Deamination Sites for Adenosine Deaminase
F. Seela, J. Ott, Bioorg. Chem., 1982, 11, 24.
57. Quantitative Affinity Chromatography of Adenosine Deaminase on Polymer-Bound Inosine: The Assessment of Binding Constants by Biospecific Elution
H. Rosemeyer, F. Seela, Anal. Biochem., 1981, 115, 339.
56. Synthese von 2-Amino-3,7-dihydro-7-(β-D-ribofuranosyl)-4H-pyrrolo[2,3-d]pyrimidin-4-on - 7-Desazaguanosin - der Stammverbindung des Nucleosids “Q“
F. Seela, D. Hasselmann, Chem. Ber., 1981, 114, 3395.
55. Die isomeren 4-Amino-N-methylpyrrolo-[2,3-d]pyrimidine
F. Seela, W. Bussmann, Chem. Ber., 1981, 114, 2056.
54. Agarose-linked Xanthosine: A Biospecific Resin for Guanine Aminohydrolase
H. Rose-meyer, F. Seela, Carbohydr. Res., 1981, 90, 53.
53. Favored Incorporation of Tubercidin in Poly (adenylic, 7-deazaadenylic acids) and their Function as Messenger Ribonucleic Acids in Protein Synthesis
F. Seela, Q.-H. Tran-Thi, H. Mentzel, V. A. Erdmann, Biochemistry, 1981, 20, 2559.
52. R- and S-Alkylidene Acetals of Adenosine: Stereochemical Probes for the Active Site of Adenosine Deaminase
J. Ott, F. Seela, Bioorg. Chem., 1981, 10, 82.
51. Selektive 7-Glykosylierung von 4-Amino-7H-pyrrolo[2,3-d]pyrimidin zu Ara-Tubercidin und dessen α-D-Anomer
F. Seela, H.-D. Winkeler, Angew. Chem., 1981, 93, 105.
50. Synthese von Ara-Tubercidin und seiner 5'-Phosphate über Phasentransfer-Glycosylierung von 4-Amino-2-methylthio-7H-pyrrolo-[2,3-d]pyrimidin
F. Seela, Q.-H. Tran Thi, H.-D. Winkeler, Chem. Ber., 1981, 114, 1217.
49. Synthese von 7-Desazainosin durch Phasentransferglycosidierung
F. Seela, D. Hasselmann, Chem. Ber., 1980, 113, 3389.
48. Ribosidierung von Pyrolo[2,3-d]pyrimidinen in Gegenwart starker Basen
F. Seela, U. Lüpke, D. Hasselmann, Chem. Ber., 1980, 113, 2808.
47. 4-Amino-7-(β-D-arabinofuranosyl)pyrrolo-[2,3-d]pyrimidin- die Synthese von Ara-Tubercidin durch Phasentransferkatalyse
H.-D. Winkeler, F. Seela, Chem. Ber., 1980, 113, 2069.
46. ‘Immobilisation of Nucleoside Antimetabolites to Polymer Resins and their Interaction with Adenosine Deaminase’
F. Seela, H. Rosemeyer, J. Ott, in ‘Enzyme Inhibitors’, Ed. U. Brodbeck, Verlag Chemie, 1980, p. 201.
45. Discadenin-Derivate ohne cytokininaktiven ∆2-Isopentenylrest
F. Seela, D. Hasselmann, Chem. Ber., 1980, 113, 2043.
44. 2'(3'),5'-Diphosphate des Nucleosids X und N3-alkylierter Uridin-Derivate
F. Seela, Q.-H. Tran Thi, Chem. Ber., 1979, 112, 3743.
43. Ribosidierung von 7H-Pyrrolo[2,3-d]pyrimidin-4(3H)-on an N-3
U. Lüpke, F. Seela, Chem. Ber., 1979, 112, 3526.
42. Bevorzugte β-Glycosidbildung durch Phasentransfer Katalyse bei der Synthese von D-Arabinofuranosyl-7-desazapurinnucleosiden
F. Seela, D. Winkeler, Angew. Chem., 1979, 91, 570.
41. Preferred β-Glycoside Formation by Phase Transfer Catalysis in the Synthesis of D-Arabinofuranosyl-7-deazapurine Nucleosides
F. Seela, D. Winkeler, Angew. Chem. Int. Ed., 1979, 18, 536.
40. Polymer-Linked 6-Azauridine-5'-Monophosphate - a Resin of High Bioaffinity to Orototidine-5'-phosphate Decarboxylase
H. Rosemeyer, F. Seela, J. Med. Chem., 1979, 22, 1545.
39. 7-(β-D-Arabinofuranosyl)pyrrolo[2,3-d]pyrimidin-4(3H)-on – das 7-Desazaderivat des antiviralen Nucleosids Ara-H
U. Lüpke, F. Seela, Chem. Ber., 1979, 112, 3432.
38. Immobilisierung von Adenosinacetalen mit variablem Alkylidenrest - die Funktion des Spacers bei enzymatischer Desaminierung
F. Seela, J. Ott, H. Rosemeyer, Z. Naturforsch., 1979, 34c, 350.
37. Synthese von L(+)Discadenin und seinem Desamino- und Descarboxy-Derivat
F. Seela, D. Hasselmann, Chem. Ber., 1979, 112, 3072.
36. Modification of the Rare Nucleoside X in Es-cherichia coli tRNAs with Antigenic Deter-mining, Photolabile and Paramagnetic residues
F. Hansske, F. Seela, K. Watanabe, F. Cramer, Methods Enzymology LIX, 1979, 166.
35. Bevorzugte O-Glykosidbildung bei der Ribosidierung von 5-Methyl-2-methylthio-7H-pyrrolo[2,3-d]pyrimidin 4(3H)-on
U. Lüpke, F. Seela, Chem. Ber., 1979, 112, 799.
34. Immobilisation of Tubercidin and Nebularine via 2',3'-Cyclic Acetals: Biospecific and Non-specific interaction of Affinity Resins with Adenosine Deaminase
H. Rosemeyer, F. Seela, Carbohydr. Res., 1979, 74, 117.
33. 3-Desamino- und 3-Descarboxyderivate des Nucleosids “X“
F. Seela, Q.-H. Tran Thi, D. Hasselmann, Chem. Ber., 1979, 112, 700.
32. Seltene Nucleoside
U. Lüpke, F. Seela, Chemie in unserer Zeit, 1978, 12, 189.
31. Aminomethylierung von 3,7-Dihydro-pyrrolo[2,3-d]pyrimidinen an C-5 - ein Weg zur Synthese von Aglycon-Analoga des Nucleosids “Q“
F. Seela, R. Richter, Chem. Ber., 1978, 111, 2925.
30. X-Ray Structure of 2',3'-0-(2-Carboxyethyl)-ethylidenadenosine – A Spacer Extended Ligand for Affinity Resins
D. Adamiak, M. Noltemeyer, W. Saenger, F. Seela, Z. Naturforsch., 1978, 33c, 169.
29. Immobilisierung von Cytidin und Uridin über 2',3'-0-cyclische Acetalderivate an Agarose
F. Seela, H. Rosemeyer, Z. Naturforsch., 1978, 33c, 56.
28. Photolabile and Paramagnetic Derivatives of the Nucleoside X and of Escherichia coli tRNAPhe
F. Hansske, K. Watanabe, F.Cramer, F. Seela, Hoppe-Seyler's Z. Physiol. Chem., 1978, 359, 1659.
27. Einfache Bestimmung der Substituentenposition im Pyrrolring von Pyrrolo[2,3-d]pyrimidinen und 7-Desazapurinnucleosiden durch 13C-NMR
U. Lüpke, F. Seela, Z. Naturforsch., 1977, 32b, 958.
26. Substrate- and Product-Affinity Resins for Adenosine Deaminase obtained by Immobilisation of Adenosine and Inosine via 2',3'-Cyclic Acetal Derivatives
H. Rosemeyer, F. Seela, Carbohydr. Res., 1978, 62, 155.
25. Introduction of antigenic determining 2,4-dinitrophenyl residues into 4-thiouridine, N3-(3-L-amino-3-carboxypropyl)uridine and tRNAPhe
E.coli, F. Seela, F. Hansske, K. Watanabe, F. Cramer, Nucleic Acids Res., 1977, 4, 711.
24. 5-Azido-ω-bromo-2-nitroacetophenone - A Crosslinking Reagent with Groups of Selective Reactivity
F. Seela, H. Rosemeyer, Hoppe-Seyler's Z. Physiol. Chem., 1977, 358, 129.
23. Mannich-Reaktion am 2-Amino-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-on, dem Chromophor des Ribonucleosids “Q“
F. Seela, U. Lüpke, Chem. Ber., 1977, 110, 1462.
22. ‘Chemical Modification of Specific Groups in tRNA’
F. Hansske, M. Kröger, F. Seela, F. Cramer, in ‘Synthesis, Structure and Chemistry of Transfer Ribonucleic Acids and their Components’, Posen, 1976, p. 55.
21. Synthese von 5-Azido-3-nitro-ω-bromacetophenon - einem photoaktivierbaren bifunktionellen Reagenz zur Vernetzung von Biopolymeren
F. Seela, Z. Naturforsch., 1976, 31c, 389.
20. Intramolekulare Katalyse des Pyrimidin-Systems bei der Hydrolyse von (Pyrimidinylthio)carbonsäureamiden
M. Kröger, F. Seela, F. Cramer, Chem. Ber., 1976, 109, 3615.
19. Polymergebundenes N-(Hexyl)-5-azido- 2-nitrobenzoesäureamid, ein photoreaktiver Träger zur Immobilisierung von Liganden
F. Seela, F. Hansske, Z. Naturforsch., 1976, 31c, 263.
18. A transition state analogue of tRNA-dependent peptide condensation as an inhibitor of ribosomal protein synthesis
F. Seela, V. A. Erdmann, Biochim. Biophys. Acta, 1976, 435, 105.
17. Darstellung und Eigenschaften von N3-(3-L-Amino-3-carboxy-propyl)uridin-5'-monophosphat - einem modifizierten Nucleotid aus Transfer-RNA
F. Seela, F. Cramer, Chem. Ber., 1976, 109, 82.
16. Synthesis of 4-Denitro-4-azido-chloramphenicol - A Photochemically Activatable Analog of Chloramphenicol
F. Seela, F. Cramer, Bioorg. Chem., 1976, 5, 25.
15. A Transition State Analogue of tRNA-Dependent Peptide Condensation
F. Seela, F. Cramer, Hoppe-Seyler's Z. Physiol. Chem., 1976, 357, 303.
14. Agarose linked adenosine and guanosine 5'-monophosphate; a new general method for the coupling of ribonucleotides to polymers through their cis-diols
F. Seela, S. Waldek, Nucleic Acids Res., 1975, 2, 2343.
13. Polymergebundenes Puromycin
F. Seela, Z. Naturforsch., 1975, 30c, 544.
12. 4-Denitro-4-azido-chloramphenicol as a “Photoaffinity Label“
F. Seela, F. Cramer, Hoppe-Seyler's Z. Physiol. Chem., 1975, 356, 1185.
11. Synthese eines Bis-Adenosin-Derivates als Analogon zum Übergangszustand der tRNA-abhängigen Peptidkondensation
F. Seela, F. Cramer, Chem. Ber., 1975, 108, 1329.
10. 4,6-Didesmethyl-4,6-dibromactinomycin C1 und 4,6-Didesmethyl-4.6-di-tert.butyl-actinomycin C1, Totalsynthese und DNA-Wechselwirkung neuer Chromopeptide; Synthese trägergebundener Actinomycin- und Serotonin-Derivate und ihre Anwendung in der Affinitätschromatographie
F. Seela, Habilitationsschrift, 1974.
9. Affinity chromatography of a serotonin binding protein from rat brain
G. A. Dette, F. Seela, W. Wesemann, Z. Klin. Chem. Klin. Biochem., 1974, 12, 243.
8. Trägergebundenes Analog des Actinomycins C1(D) und Affinitätschromatographie von Nucleinsäuren
F. Seela, Z. Naturforsch., 1974, 29c, 521.
7. Trägergebundene Serotoninderivate und Affinitätschromatographie synaptischer Membranproteine
F. Seela, W. Wesemann, Z. Naturforsch., 1974, 29c, 248.
6. 4,6-Didemethyl-4,6-dibromoactinomycin C1 (D)
F. Seela, J. Med. Chem., 1972, 15, 684.
5. 4,6-Didesmethyl-actinomycin C1 und dessen 4,6-Dimethoxy-, 4,6-Diäthyl- und 4,6-Ditert.butyl-Derivat
H. Brockmann, F. Seela, Chem. Ber., 1971, 104, 2751.
4. Actinomin und 4,6-Didesmethyl-4,6-di-tert.-butylactinomin-Modellverbindungen zum Studium der Actinomycin/DNA-Wechselwirkung
F. Seela, Z. Naturforsch., 1971, 26b, 875.
3. Synthese von 4,6-Didesmethyl-4,6-dimethoxy-actinomycin C1
H. Brockmann, F. Seela, Tetrahedron Lett., 1968, 2, 161.
2. Totalsynthese strukturvarianter Actinomycine mit modifiziertem Chromophor
F. Seela, Dissertation, Universität Göttingen, 1967.
1. Synthese von 1,8-Didesmethylactinomycin C1
H. Brockmann, F. Seela, Tetrahedron Lett., 1965, 52, 4803.